Professor Paul Newton

Head of Medicine Quality Research Group

http://www.tropmedres.ac/lomwru-laos

paul.newton@iddo.org

RESEARCH THEME(S)

Medicine quality

WWARN

Malaria

BIOGRAPHY

Professor Paul Newton is Head of the IDDO Medicine Quality Research Group. He was appointed Head of the WorldWide Antimalarial Research Network (WWARN) Antimalarial Quality Group in 2010. He was the founding Director of the Lao-Oxford-Mahosot-Wellcome Trust Research Unit (LOMWRU) in the Microbiology Laboratory of Mahosot Hospital in Vientiane, Laos, from 2000 to 2019 and now works based from Oxford. After junior doctor training in infectious disease and internal medicine in the UK, he worked in the Mahidol Oxford Research Unit in Bangkok on malaria and melioidosis for four years before moving to Laos.

Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Southern Asia and South-eastern Asia, 1980-2015

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia

Quality assurance of drugs used in clinical trials: proposal for adapting guidelines

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis

Mind the gaps - the epidemiology of poor-quality anti-malarials in the malarious world - analysis of the WorldWide Antimalarial Resistance Network database

Falsified medicines in Africa: all talk, no action

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

Mind the gaps - The epidemiology of poor-quality anti-malarials in the malarious world - Analysis of the WorldWide Antimalarial Resistance Network database

The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Causes of non-malarial fever in Laos: a prospective study

Evaluation of a Simple Blood Culture Amplification and Antigen Detection Method for Diagnosis of Salmonella enterica Serovar Typhi Bacteremia

A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia.

Causes of community-acquired bacteremia and patterns of antimicrobial resistance in Vientiane, Laos.

Counterfeit anti-infective drugs

Manslaughter by fake artesunate in Asia - will Africa be next?

Rickettsial infections and fever, Vientiane, Laos.

Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria.

Fake artesunate in southeast Asia

Neglected rickettsial diseases in Southeast Asia: Twenty-five years of progress in surveillance, diagnostics, and clinical research

A repetitive nucleotide insertion in the rplV gene is associated with in vitro resistance to azithromycin in Rickettsia typhi

Comparison of in vitro antibiotic susceptibility testing of R. typhi using plaque assay and quantitative real-time PCR.

Leptospirosis Incidence at Four Sites in Sub-Saharan Africa and South East Asia: An International Multi-Site Hybrid Surveillance Study

Targeting surface cell antigen 2 increases sensitivity of Rickettsia typhi detection

Biochemical profiling provides a low-cost and globally accessible method to detect falsified vaccines and insulin

Complete genomes of Rickettsia typhi reveal a clonal population

The epidemiology and clinical features of melioidosis in the Lao PDR: a 21-year prospective hospital-based cohort study

The spatiotemporal distribution of substandard and falsified antimalarial medicines in Africa, 1996-2019

Rapid screening of ethylene glycol and diethylene glycol in raw materials and medicinal syrups using low-cost field deployable assays

Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines

Pharmabiome analyses in tandem with chemometrics can help trace the provenance of falsified medicines: a proof-of-concept study

Leptospirosis in the United Kingdom: a decade of experience from a large regional hospital

Leptospirosis Prevalence and Risk Factors Among Patients Presenting With Fever to 4 Healthcare Sites in Sub-Saharan Africa and South East Asia: An International Multisite Observational and Nested Case–Control Study

Spatio-temporal distribution of extended spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae blood stream infections in Laos

Low-research settings: is there a need for specific attention from funders?

Detection of Mycoplasma pneumoniae in hospitalized children with pneumonia in Laos

IgG Antibodies to Pneumococcal Serotypes 1 and 5 in Relation to PCV13 Vaccination Status in Children Aged Under 5 Years in Lao PDR: A Cross-Sectional Survey

Screening for visceral leishmaniasis in humans and animals in Laos

Systematic scoping review of the noma evidence landscape: current knowledge and gaps

Estimating scrub typhus and murine typhus incidence among adolescents and adults in Yangon, Myanmar

Prevalence and risk factors for murine typhus, scrub typhus, and spotted fever group rickettsioses among adolescent and adult patients presenting to Yangon General Hospital, Yangon, Myanmar

Evolution and significance of neuronal surface autoantibodies after Japanese encephalitis

Handheld spatially offset raman spectroscopy for rapid non-invasive detection of ethylene glycol and diethylene glycol in medicinal syrups

Pneumococcal density and respiratory co-detection in severe pediatric pneumonia in Laos

Genetic surveillance of Plasmodium falciparum populations following treatment policy revisions in the Greater Mekong Subregion

Detection of Mycoplasma pneumoniae in hospitalized children with pneumonia in Laos

Hide and seek with falsified medicines: current challenges and physico-chemical and biological approaches for tracing the origin of trafficked products

Detection of Mycoplasma pneumoniae in hospitalized children with pneumonia in Laos

A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity

Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry

A systematic review of the noma evidence landscape: current knowledge and gaps

The Public Health Issue of Falsified and Substandard Medicines in Resource-Limited Settings

EVALUATING THE IMPACT OF A LAO LANGUAGE MOBILE PHONE APPLICATION ON ADHERENCE TO ANTIMICROBIAL PRESCRIBING GUIDELINES IN LAO PDR

Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in Laos

Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening

Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from China, 1980–2015

Stable isotope ratio analysis: an emerging tool to trace the origin of falsified medicines

Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in the Laos

Forensic investigation of falsified antimalarials using isotope ratio mass spectrometry: a pilot investigation

Repurposing rapid diagnostic tests to detect falsified vaccines in supply chains

Estimating the subnational prevalence of antimicrobial resistant Salmonella enterica serovars Typhi and Paratyphi A infections in 75 endemic countries, 1990–2019: a modelling study

Diagnosis of human leptospirosis: systematic review and meta-analysis of the diagnostic accuracy of the Leptospira microscopic agglutination test, PCR targeting Lfb1, and IgM ELISA to Leptospira fainei serovar Hurstbridge

Identification of Burkholderia cepacia strains that express a Burkholderia pseudomallei-like capsular polysaccharide

Implementing the WHO AWaRe antibiotic book guidance in lower-resource settings: the case of the Lao PDR

6 Medical Products Quality and Public Health

Genetic surveillance of Plasmodium falciparum populations following treatment policy revisions in the Greater Mekong Subregion

Innovative method for rapid detection of falsified COVID-19 vaccines through unopened vials using handheld Spatially Offset Raman Spectroscopy (SORS)

The uncertain role of substandard and falsified medicines in the emergence and spread of antimicrobial resistance

Longitudinal comparison of bacterial pathogen seropositivity among wet market vendors in the Lao People's Democratic Republic

Is this pill an antibiotic or a painkiller? Improving the identification of oral antibiotics for better use

Estimating the prevalence of poor-quality anti-TB medicines: a neglected risk for global TB control and resistance

Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection

The highly diverse plasmid population found in Escherichia coli colonizing travellers to Laos and its role in antimicrobial resistance gene carriage

The quality of antiretroviral medicines: an uncertain problem

Bartonella species in Cambodia, Ghana, Laos, and Peru: results from vector and sero-surveys

The epidemiology of substandard and falsified vaccines and innovation for their detection in supply chains

A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations

Environmental DNA as an innovative technique to identify the origins of falsified antimalarial tablets-a pilot study of the pharmabiome

Ten-year persistence and evolution of Plasmodium falciparum antifolate and anti-sulfonamide resistance markers pfdhfr and pfdhps in three Asian countries

Malaria outbreak in Laos driven by a selective sweep for Plasmodium falciparum kelch13 R539T mutants: a genetic epidemiology analysis

MORU Tropical Health Network annual report 2021

Orientia tsutsugamushi in chiggers and small mammals in Laos

Renewed risk for epidemic typhus related to war and massive population displacement, Ukraine

Substandard and falsified antibiotics: neglected drivers of antimicrobial resistance?

The quality of veterinary medicines and their implications for One Health

Antimicrobial resistance patterns in bacteria causing febrile illness in Africa, South Asia, and Southeast Asia: a systematic review of published etiological studies from 1980-2015

Evaluation of trends in hospital antimicrobial use in the Lao PDR using repeated point-prevalence surveys-evidence to improve treatment guideline use

Childhood encephalitis in the Greater Mekong region (the SouthEast Asia Encephalitis Project): a multicentre prospective study

Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia

Immunoglobulin M seroneutralization for improved confirmation of Japanese encephalitis virus infection in a flavivirus-endemic area

A one-health sampling strategy to explore the dissemination and relationship between colistin resistance in human, animal, and environmental sectors in Laos

Detection and significance of neuronal autoantibodies in patients with meningoencephalitis in Vientiane, Lao PDR

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

Out of the boxes, out of the silos: The need of interdisciplinary collaboration to reduce poor-quality medical products in the supply chain

Zoonotic pathogens in wildlife traded in markets for human consumption, Laos

Flavivirus cross-reactivity would explain the apparent findings of Japanese encephalitis virus infection in Nigeria

A random survey of the prevalence of falsified and substandard antibiotics in the Lao PDR

A case-control study of the causes of acute respiratory infection among hospitalized patients in Northeastern Laos

15 A 3-Year-Old Boy from Laos With Right Suppurative Parotitis

Trends in Hospital Antimicrobial Use in the Lao PDR Using Regular Point-Prevalence Surveys-Evidence to Evaluate and Improve Treatment Guideline Use

15 A 3-Year-Old Boy from Laos With Right Suppurative Parotitis

A One-Health Sampling Strategy to Explore the Dissemination and Relationship Between Colistin Resistance in Human, Animal, and Environmental Sectors in Laos

Genetic analysis of a malaria outbreak in Laos driven by a selective sweep for Plasmodium falciparum kelch13 R539T mutants

Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection

Genetic diversity of Leptospira isolates in Lao PDR and genome analysis of an outbreak strain

Antimicrobial use and resistance data in human and animal sectors in the Lao PDR: evidence to inform policy

Evolution of multidrug resistance in Plasmodium falciparum: A longitudinal study of genetic resistance markers in the Greater Mekong subregion

A comparison of surface and total deltamethrin levels of insecticide-treated nets and estimation of the effective insecticidal lifetime

A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations

The main pathogens causing febrile illness and implications for fever management in Laos; results from the Fiebre study

Development and performance evaluation of a low-cost, high throughput, multiplex immunoassay of thirteen fever severity and etiology markers

Etiology of febrile neurological syndromes in low- and middle-income countries: results from the Fiebre study

Orientia tsutsugamushi dynamics in vectors and hosts: ecology and risk factors for foci of scrub typhus transmission in northern Thailand

Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform

Multiphase evaluation of portable medicines quality screening devices

Implementation of field detection devices for antimalarial quality screening in Lao PDR-A cost-effectiveness analysis

A comparative field evaluation of six medicine quality screening devices in Laos

Laboratory evaluation of twelve portable devices for medicine quality screening

Evaluation of portable devices for medicine quality screening: Lessons learnt, recommendations for implementation, and future priorities

The quality of medical products for cardiovascular diseases: a gap in global cardiac care

Measuring pneumococcal conjugate vaccine impact in a low-resource setting with minimal baseline data

Pneumococcal conjugate vaccine is effective against hypoxic pneumonia in Laos, Mongolia and Papua New Guinea

Clustering of malaria in households in the Greater Mekong Subregion: operational implications for reactive case detection

A spatio-temporal analysis of scrub typhus and murine typhus in Laos; implications from changing landscapes and climate

Evaluation strategies for measuring pneumococcal conjugate vaccine impact in low-resource settings

Dengue diagnostic test use to identify Aedes-borne disease hotspots

Genetic surveillance in the Greater Mekong subregion and South Asia to support malaria control and elimination

Preprints in times of COVID19: the time is ripe for agreeing on terminology and good practices

Sounding out falsified medicines from genuine medicines using Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS)

Indirect effects of 13-valent pneumococcal conjugate vaccine on pneumococcal carriage in children hospitalised with acute respiratory infection despite heterogeneous vaccine coverage: an observational study in Lao People's Democratic Republic

The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response

Rickettsial infections: A blind spot in our view of neglected tropical diseases

Nasopharyngeal pneumococcal colonization density is associated with severe pneumonia in young children in the Lao People’s Democratic Republic

Molecular detection of pathogens in negative blood cultures in the Lao People’s Democratic Republic

Targeted capture and sequencing of Orientia tsutsugamushi genomes from chiggers and humans

Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia

Dynamics of intestinal multidrug-resistant bacteria colonisation contracted by visitors to a high-endemic setting: a prospective, daily, real-time sampling study

Impact of delays to incubation and storage temperature on blood culture results: a multi-centre study

Whole-genome assemblies of 16 Burkholderia pseudomallei isolates from rivers in Laos

Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform

Outcome of Japanese Encephalitis Virus (JEV) infection in pediatric and adult patients at Mahosot Hospital, Vientiane, Lao PDR

Diagnostic accuracy of an in-house Scrub Typhus enzyme linked immunoassay for the detection of IgM and IgG antibodies in Laos.

Impact of delays to incubation and storage temperature on blood culture results in tropical countries: A multi-centre study

The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network

How many human pathogens are there in Laos? An estimate of national human pathogen diversity and analysis of historical trends.

The isolation of Orientia tsutsugamushi and Rickettsia typhi from human blood through mammalian cell culture – a descriptive series of 3,227 samples and outcomes in the Lao PDR

Comparison of thiamin diphosphate high-performance liquid chromatography and erythrocyte transketolase assays for evaluating thiamin status in malaria patients without beriberi

Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Southern Asia and South-eastern Asia, 1980-2015

Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980–2015

Febrile illness mapping-much of the world without data and without evidence-based treatments

A systematic review of the untreated mortality of murine typhus.

The effectiveness of the 13-valent pneumococcal conjugate vaccine against hypoxic pneumonia in children in Lao People's Democratic Republic: An observational hospital-based test-negative study

Perception of health risks in Lao market vendors

Genetic surveillance in the Greater Mekong Subregion and South Asia to support malaria control and elimination

Marginalized mites: Neglected vectors of neglected diseases

Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE): protocol for a multisite prospective observational study of the causes of fever in Africa and Asia

Baseline results of a living systematic review for COVID-19 clinical trial registrations

Point-of-care ultrasound in the diagnosis of melioidosis in Laos

Spatial epidemiology of Japanese encephalitis virus and other infections of the central nervous system infections in Lao PDR (2003-2011): A retrospective analysis

COVID-19 and risks to the supply and quality of tests, drugs, and vaccines

Selection of diagnostic cutoffs for murine typhus IgM and IgG immunofluorescence assay: a systematic review

A need to raise the bar - A systematic review of temporal trends in diagnostics for Japanese encephalitis virus infection, and perspectives for future research

Harnessing gengue rapid diagnostic tests for the combined surveillance of Dengue, Zika, and Chikungunya Viruses in Laos

Bacteremia caused by extended-spectrum beta-lactamase–producing Enterobacteriaceae in Vientiane, Lao PDR: a 5-year study

Estimation of incidence of typhoid and paratyphoid fever in Vientiane, Lao People's Democratic Republic

Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials

Typhoid in Laos: An 18-year perspective

Correction to: The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR.

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

A 72-Year-Old Male Farmer from Laos With Extensive Skin Lesions on the Lower Leg

A 30-Year-Old Male Chinese Trader With Fever in Laos

A 2-Month-Old Girl from Laos With Dyspnoea, Cyanosis and Irritability

Baseline results of a living systematic review for COVID-19 clinical trial registrations.

68 Scrub Typhus

A 30-Year-Old Male Chinese Trader With Fever in Laos

A 72-Year-Old Male Farmer from Laos With Extensive Skin Lesions on the Lower Leg

A 2-Month-Old Girl from Laos With Dyspnoea, Cyanosis and Irritability

Drug-resistant scrub typhus

Biosafety and biosecurity requirements for Orientia spp. diagnosis and research: recommendations for risk-based biocontainment, work practices and the case for reclassification to risk group 2

Oxford nanopore MinION sequencing enables rapid whole genome assembly of rickettsia typhi in a resource-limited setting

Global access to quality-assured medical products: the Oxford Statement and call to action

Real-time sampling of travelers shows intestinal colonization by multidrug-resistant bacteria to be a dynamic process with multiple transient acquisitions

Scrub typhus ecology: a systematic review of Orientia in vectors and hosts

The temporal dynamics of humoral immunity to Rickettsia typhi infection in murine typhus patients

Evaluation of the Active Melioidosis Detect™ test as a point-of-care tool for the early diagnosis of melioidosis: a comparison with culture in Laos

Scrub typhus and the misconception of doxycycline resistance

Quality of medical products for diabetes management: a systematic review

Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review.

Meta-transcriptomic identification of hepatitis B virus in cerebrospinal fluid in patients with central nervous system disease

The 13-Valent Pneumococcal Conjugate Vaccine Is Effective Against Hypoxic Pneumonia in Children in Lao PDR: A Novel Method Using a Hospital-Based Observational Study

Comparison of two commercial ELISA kits for the detection of anti-dengue IgM for routine dengue diagnosis in Laos

The cost-effectiveness of the use of selective media for the diagnosis of melioidosis in different settings

One hypervirulent clone, sequence type 283, accounts for a large proportion of invasive Streptococcus agalactiae isolated from humans and diseased tilapia in Southeast Asia

Rapid diagnostic tests as a source of dengue virus RNA for envelope gene amplification: a proof of concept

Nasal or throat sampling is adequate for the detection of the human respiratory syncytial virus in children with acute respiratory infections

A random survey of the prevalence of falsified and substandard antibiotics in the Lao PDR

Management of Central Nervous System Infections, Vientiane, Laos, 2003–2011

Treatment-seeking behaviour for febrile illnesses and its implications for malaria control and elimination in Savannakhet Province, Lao PDR (Laos): a mixed method study

Toward a quantification of risks at the nexus of conservation and health: The case of bushmeat markets in Lao PDR

Whole cell matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of Leptospira spp. in Thailand and Lao PDR

“Epidemiology and aetiology of influenza-like illness among households in metropolitan Vientiane, Lao PDR”: A prospective, community-based cohort study

Determining the pneumococcal conjugate vaccine coverage required for indirect protection within Asia and the Pacific: a prospective observational study

A robust incubator to improve access to microbiological culture in low resource environments

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from south and southeast Asia

Viral RNA Degradation Makes Urine a Challenging Specimen for Detection of Japanese Encephalitis Virus in Patients With Suspected CNS Infection

Low Zika virus seroprevalence in Vientiane, Laos, 2003-2015

Molecular characterization and mapping of glucose-6-phosphate dehydrogenase (G6PD) mutations in the Greater Mekong Subregion

Defining system requirements for simplified blood culture to enable widespread use in resource-limited settings

Accounting for aetiology: can regional surveillance data alongside host biomarker-guided antibiotic therapy improve treatment of febrile illness in remote settings?

Geographic, environmental, and demographic correlates of central nervous system infections in Lao PDR (2003 – 2011): a retrospective secondary spatial analysis

Correction: "Epidemiology and aetiology of influenza-like illness among households in metropolitan Vientiane, Lao PDR": A prospective, community-based cohort study.

PORTABLE SCREENING DEVICES TO ASSESS MEDICINES QUALITY FOR NATIONAL MEDICINES REGULATORY AUTHORITIES

FIEBRE (FEBRILE ILLNESS EVALUATION IN A BROAD RANGE OF ENDEMICITIES): A MULTI-SITE PROSPECTIVE OBSERVATIONAL STUDY OF CAUSES OF FEVER IN SUB-SAHARAN AFRICA AND SOUTHEAST ASIA

EXPANDED FEVER SURVEILLANCE AMONG PROVINCIAL HOSPITALS IN THE LAO PEOPLE'S DEMOCRATIC REPUBLIC

The 13-Valent Pneumococcal Conjugate Vaccine Is Effective Against Hypoxic Pneumonia in Children in Lao PDR: A Novel Method Using a Hospital-Based Observational Study

Perceptions of asymptomatic malaria infection and their implications for malaria control and elimination in Laos

Evaluation of consensus method for the culture of Burkholderia pseudomallei in soil samples from Laos

The dynamic of asymptomatic Plasmodium falciparum infections following mass drug administrations with dihydroarteminisin-piperaquine plus a single low dose of primaquine in Savannakhet Province, Laos

Tick-transmitted human infections in Asia

Novel high-throughput screening method using quantitative PCR to determine the antimicrobial susceptibility of Orientia tsutsugamushi clinical isolates

Corrigendum: Comparative pan-genomic analyses of Orientia tsutsugamushi reveal an exceptional model of bacterial evolution driving genomic diversity.

Field detection devices for screening the quality of medicines: a systematic review

Laboratory-acquired scrub typhus and murine typhus infections: The argument for risk-based approach to biosafety requirements for Orientia tsutsugamushi and Rickettsia typhi laboratory activities

Climatic drivers of melioidosis in Laos and Cambodia: a 16-year case series analysis

Streptococcus agalactiae ST283 has been present in Laos for over 18 years

Comparative pan-genomic analyses of Orientia tsutsugamushi reveal an exceptional model of bacterial evolution driving genomic diversity

A prospective, open-label, randomized trial of doxycycline versus azithromycin for the treatment of uncomplicated murine typhus

Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias

Triboelectric nanogenerator (TENG) mass spectrometry of falsified antimalarials

Comparison of glucose-6 phosphate dehydrogenase status by fluorescent spot test and rapid diagnostic test in Lao PDR and Cambodia

Rivers as carriers and potential sentinels for Burkholderia pseudomallei in Laos

Detection of Japanese encephalitis virus RNA in human throat samples in Laos – a pilot study

Determining the pneumococcal conjugate vaccine coverage required for indirect protection against vaccine-type pneumococcal carriage in low and middle-income countries: a protocol for a prospective observational study

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

Oxford Nanopore MinION sequencing enables rapid whole-genome assembly of Rickettsia typhi in a resource-limited setting

Oxford Nanopore MinION sequencing enables rapid whole-genome assembly of Rickettsia typhi in a resource-limited setting

Antibiotics and activity spaces: protocol of an exploratory study of behaviour, marginalisation and knowledge diffusion

Febrile illness in Asia: gaps in epidemiology, diagnosis, management for informing health policy

Development of an improved RT-qPCR Assay for detection of Japanese encephalitis virus (JEV) RNA including a systematic review and comprehensive comparison with published methods.

A prospective hospital study to evaluate the diagnostic accuracy of rapid diagnostic tests for the early detection of leptospirosis in Laos

Association between reported aetiology of central nervous system infections and the speciality of study investigators-a bias compartmental syndrome?

Melioidosis in the Lao People’s Democratic Republic

Azithromycin resistance in Shigella spp. in Southeast Asia

Non-typhoidal Salmonella serovars associated with invasive and non-invasive disease in the Lao People's Democratic Republic

Why do people participate in mass anti-malarial administration? Findings from a qualitative study in Nong District, Savannakhet Province, Lao PDR (Laos)

COST-EFFECTIVENESS ANALYSIS OF MEDICINE QUALITY SCREENING DEVICES IN LAOS

Spontaneous emergence of a gnathostoma spinigerum adult worm from the abdominal skin of a laotian woman: A case report

COME RAIN OR COME SHINE. DIFFERENTIAL SPATIOTEMPORAL DYNAMICS OF SCRUB TYPHUS AND MURINE TYPHUS IN THE LAO PDR

PRELIMINARY PERFORMANCE OF THE BIOFIRE® FILMARRAY® TRAVEL-RELATED FEBRILE ILLNESS PANEL AT THE MAHOSOT HOSPITAL IN VIENTIANE, LAOS

ACUTE RESPIRATORY INFECTION SURVEILLANCE IN A PHASE 2 PROSPECTIVE, COMMUNITY-BASED COHORT IN VIENTIANE, LAOS

A MIXED METHOD STUDY OF HEALTH SEEKING BEHAVIOR FOR FEBRILE ILLNESSES AND ITS IMPLICATIONS FOR MALARIA CONTROL AND ELIMINATION IN SAVANNAKHET PROVINCE, LAO PDR

Evaluation of consensus method for the culture of Burkholderia pseudomallei in soil samples from Laos.

Molecular epidemiology of dengue viruses in three provinces of Lao PDR, 2006-2010.

When it just won't go away: oral artemisinin monotherapy in Nigeria, threatening lives, threatening progress

Enrolling pregnant women in research: ethical challenges encountered in Lao PDR (Laos)

Poor performance of two rapid immunochromatographic assays for anti-Japanese encephalitis virus immunoglobulin M detection in cerebrospinal fluid and serum from patients with suspected Japanese encephalitis virus infection in Laos

Angiostrongylus cantonensis DNA in Cerebrospinal Fluid of Persons with Eosinophilic Meningitis, Laos

A comparison of two molecular methods for diagnosing leptospirosis from three different sample types in patients presenting with fever in Laos

Rickettsial neurological infections

Estimating the burden of scrub typhus: A systematic review

Evaluation of screening technologies for assessing medicine quality

Clostridium difficile infection in the Lao People's Democratic Republic: first isolation and review of the literature.

Acute respiratory infections in hospitalized children in Vientiane, Lao PDR - the importance of Respiratory Syncytial Virus

Burkholderia pseudomallei in a lowland rice paddy: seasonal changes and influence of soil depth and physico-chemical properties.

Molecular epidemiology of Staphylococcus aureus skin and soft tissue infections in the Lao People's Democratic Republic

Do anti-malarials in Africa meet quality standards? The market penetration of non quality-assured artemisinin combination therapy in eight African countries

Role of medicines of unknown identity in adverse drug reaction-related hospitalizations in developing countries: Evidence from a cross-sectional study in a teaching hospital in the Lao People's Democratic Republic.

Antimicrobial susceptibility testing of Leptospira spp. in the Lao People’s Democratic Republic using disk diffusion

128 Scrub Typhus and Other Tropical Rickettsioses

Temperature of a dengue rapid diagnostic test under tropical climatic conditions: a follow up study

Febrile illness in adolescents and adults

TARGET PRODUCT PROFILE FOR A DIAGNOSTIC ASSAY TO DIFFERENTIATE BETWEEN BACTERIAL AND NON-BACTERIAL INFECTIONS TO GUIDE ANTIMICROBIALS USE IN RESOURCE-LIMITED SETTINGS: AN EXPERT CONSENSUS

A ROBUST INCUBATOR TO FACILITATE MORE WIDESPREAD BACTERIAL CULTURE FOR LOW RESOURCE ENVIRONMENTS IN DEVELOPING COUNTRIES

THE MOLECULAR EPIDEMIOLOGY OF STAPHYLOCOCCUS AUREUS SKIN AND SOFT TISSUE INFECTIONS IN THE LAO PEOPLE'S DEMOCRATIC REPUBLIC

NEUROLOGICAL OUTCOMES OF JAPANESE ENCEPHALITIS VIRUS INFECTION IN PEDIATRIC AND ADULT PATIENTS AT MAHOSOT HOSPITAL, VIENTIANE, LAO PDR

128 Scrub Typhus and Other Tropical Rickettsioses

Detection of A. cantonensis by qPCR in Laos

An epidemic of dystonic reactions in central Africa.

Fake penicillin, The Third Man, and Operation Claptrap.

Prototype Positive Control Wells for Malaria Rapid Diagnostic Tests: Prospective Evaluation of Implementation among Health Workers in Lao People's Democratic Republic and Uganda.

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia

Health risks of unknown medicines: evidence from adverse drug reactions in Laos

The first Science Café in Laos

Predictable threats to public health through delaying universal access to innovative medicines for Hepatitis C: A pharmaceutical standpoint

Geographic distribution of amino acid mutations in DHFR and DHPS in Plasmodium vivax isolates from Lao PDR, India and Colombia

Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus.

Large-scale survey for tickborne bacteria, Khammouan Province, Laos

Fingerprinting of falsified artemisinin combination therapies via direct analysis in real time coupled to a compact single quadrupole mass spectrometer

Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)

Ethical challenges in designing and conducting medicine quality surveys

Correction: The Diversity and Geographical Structure of Orientia tsutsugamushi Strains from Scrub Typhus Patients in Laos.

Using rapid diagnostic tests as a source of viral RNA for dengue serotyping by RT-PCR - a novel epidemiological tool

A link between poor quality antimalarials and malaria drug resistance?

The aetiologies and impact of fever in pregnant inpatients in Vientiane, Laos

Modelling the impact and cost-effectiveness of biomarker tests as compared with pathogen-specific diagnostics in the management of undifferentiated fever in remote tropical settings

Dried cerebrospinal fluid spots for diagnosing Japanese Encephalitis Virus (JEV) infection by Anti-JEV IgM antibody capture enzyme-linked immunosorbent assay: Harnessing the potential of a fully saturated pre-cut filter paper disc

Pre-cut Filter Paper for Detecting Anti-Japanese Encephalitis Virus IgM from Dried Cerebrospinal Fluid Spots

Adverse drug reaction-related hospitalizations of adults in the Lao People's Democratic Republic: health risks of unknown medicines

Population Structure Shapes Copy Number Variation in Malaria Parasites

The utility of blood culture fluid for the molecular diagnosis of Leptospira: A prospective evaluation

Land use and soil type determine the presence of the pathogen Burkholderia pseudomallei in tropical rivers.

Prevalence of malaria in pregnancy in southern Laos: a cross-sectional survey.

Blood Culture-Negative Endocarditis

Survival and growth of Orientia tsutsugamushi in conventional hemocultures

Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria

Investigation of recurrent melioidosis in Lao People's Democratic Republic by multilocus sequence typing

Accuracy of commercially available c-reactive protein rapid tests in the context of undifferentiated fevers in rural Laos.

Population awareness of risks related to medicinal product use in Vientiane Capital, Lao PDR: a cross-sectional study for public health improvement in low and middle income countries

How many patients with anti-JEV IgM in cerebrospinal fluid really have Japanese encephalitis?

Leeches as further potential vectors for rickettsial infections

Performance of C-reactive protein and procalcitonin to distinguish viral from bacterial and malarial causes of fever in Southeast Asia

Counterfeit antiepileptic drugs threaten community services in Guinea-Bissau and Nigeria

How to optimally diagnose orientia tsutsugamushi or rickettsia typhi infections in patients with central nervous system disease?

Causes of Fever in Rural Southern Laos

Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos

The Diversity and Geographical Structure of Orientia tsutsugamushi Strains from Scrub Typhus Patients in Laos

A systematic review of mortality from untreated scrub typhus (Orientia tsutsugamushi)

Blood–Brain Barrier Function and Biomarkers of Central Nervous System Injury in Rickettsial Versus Other Neurological Infections in Laos

Neorickettsia sennetsu as a Neglected Cause of Fever in South-East Asia

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

Temperature and the Field Stability of a Dengue Rapid Diagnostic Test in the Tropics

Erratum for Parry et al., Clinically and Microbiologically Derived Azithromycin Susceptibility Breakpoints for Salmonella enterica Serovars Typhi and Paratyphi A

A Systematic Review of the Mortality from Untreated Leptospirosis

A Repeat Random Survey of the Prevalence of Falsified and Substandard Antimalarials in the Lao PDR: A Change for the Better

Responding to the Pandemic of Falsified Medicines

Collaborative Health and Enforcement Operations on the Quality of Antimalarials and Antibiotics in Southeast Asia

Integration of Novel Low-Cost Colorimetric, Laser Photometric, and Visual Fluorescent Techniques for Rapid Identification of Falsified Medicines in Resource-Poor Areas: Application to Artemether–Lumefantrine

Estimated Under-Five Deaths Associated with Poor-Quality Antimalarials in Sub-Saharan Africa

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

Evaluation of molecular methods to improve the detection of Burkholderia pseudomallei in soil and water samples from Laos.

Colonization with Enterobacteriaceae producing ESBLs in children attending pre-school childcare facilities in the Lao People's Democratic Republic.

Genomic epidemiology of the current wave of artemisinin resistant malaria

Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A.

A novel technique for detecting antibiotic-resistant typhoid from rapid diagnostic tests.

Antibiotic prescription behaviours in Lao People's Democratic Republic: a knowledge, attitude and practice survey

Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia

Quality assurance of drugs used in clinical trials: proposal for adapting guidelines

High Prevalence of Tropheryma whipplei in Lao Kindergarten Children

Infective endocarditis in the Lao PDR: Clinical characteristics and outcomes in a developing country

Orientia, rickettsia, and leptospira pathogens as causes of CNS infections in Laos: a prospective study

An expanded taxonomy of hepatitis C virus genotype 6: characterization of 22 new full-length viral genomes

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Genetic architecture of artemisinin-resistant Plasmodium falciparum

Melioidosis in Laos

Mapping fever aetiologies in malaria-endemic areas: an interactive, open-access, on-line map

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis

Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data

DEVELOPMENT OF ANTIBODY-BASED IMMUNO-ASSAYS FOR QUALITY CONTROL OF ARTEMISININ-BASED COMBINATION THERAPIES

HUMORAL IMMUNITY CONTRIBUTES TO CLEARANCE OF ARTEMISININ-RESISTANT PARASITES IN SOUTHEAST ASIA

LARGE-SCALE SCANS FOR GENOMIC REGIONS UNDER POSITIVE SELECTION IN SOUTHEAST ASIAN PLASMODIUM FALCIPARUM REVEAL GENES OF PUBLIC HEALTH IMPORTANCE

PATHOGEN-SPECIFIC FEATURES OF THE HUMAN PERIPHERAL BLOOD TRANSCRIPTIONAL PROFILE IN PATIENTS WITH SCRUB TYPHUS AND MURINE TYPHUS

Prototype positive control wells for malaria rapid diagnostic tests: training effectiveness, impact on RDT use and health worker perceptions in Lao PDR and Uganda

A 72-year-old Male Farmer from Laos with Extensive Skin Lesions on the Lower Leg

A 30-year-old Male Trader from China with Persistent Fever

A 2-month-old Girl from Laos with Dyspnoea, Cyanosis and Irritability

A 3-year-old Boy from Laos with Right Suppurative Parotitis

A 72-year-old Male Farmer from Laos with Extensive Skin Lesions on the Lower Leg

A 30-year-old Male Trader from China with Persistent Fever

A 3-year-old Boy from Laos with Right Suppurative Parotitis

A 2-month-old Girl from Laos with Dyspnoea, Cyanosis and Irritability

Group A streptococcal strains isolated in Lao People's Democratic Republic from 2004 to 2013

The use of dried cerebrospinal fluid filter paper spots as a substrate for PCR diagnosis of the aetiology of bacterial meningitis in the Lao PDR

Bartonella henselae endocarditis in Laos - 'The unsought will go undetected'

Thiamin supplementation does not reduce the frequency of adverse events after anti-malarial therapy among patients with falciparum malaria in southern Laos

Mind the gaps - the epidemiology of poor-quality anti-malarials in the malarious world - analysis of the WorldWide Antimalarial Resistance Network database

Europe and the United Nations: Clinical Trials, Not Criminal Trials

First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR

Evaluation of a New Handheld Instrument for the Detection of Counterfeit Artesunate by Visual Fluorescence Comparison

Cost of treating inpatient falciparum malaria on the Thai-Myanmar border

Trimethoprim/sulfamethoxazole resistance in Burkholderia pseudomallei

Falsified medicines in Africa: all talk, no action

Rickettsia felis Infections and Comorbid Conditions, Laos, 2003–2011 - Volume 20, Number 8—August 2014 - Emerging Infectious Diseases journal - CDC

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

SU‐E‐J‐115: Using Markov Chain Modeling to Elucidate Patterns in Breast Cancer Metastasis Over Time and Space

A tiered analytical approach for investigating poor quality emergency contraceptives

Mind the gaps - The epidemiology of poor-quality anti-malarials in the malarious world - Analysis of the WorldWide Antimalarial Resistance Network database

Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries

Defining the geographical range of the Plasmodium knowlesi reservoir.

SYBR green real-time PCR for the detection of all enterovirus-A71 genogroups

Loop-Mediated Isothermal Amplification for Rickettsia typhi (the Causal Agent of Murine Typhus): Problems with Diagnosis at the Limit of Detection

An Overview of the Clinical Use of Filter Paper in the Diagnosis of Tropical Diseases

Epidemiology of Bacteremia in Young Hospitalized Infants in Vientiane, Laos, 2000–2011

Estimating the burden of Japanese encephalitis virus and other encephalitides in countries of the mekong region

Visual identification of single units of medicines for pharmacoepidemiological studies in developing countries: a pilot study in Lao PDR

Healthcare providers and population's knowledge regarding the risks related to medicinal products use: a cross-sectional study conducted in Laos

CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial.

Ambient mass spectrometry technologies for the detection of falsified drugs

The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Concurrent infection with murine typhus and scrub typhus in southern Laos--the mixed and the unmixed

An epidemic of dengue-1 in a remote village in rural Laos

Causes of non-malarial fever in Laos: a prospective study

Diversity of the 47-kD HtrA Nucleic Acid and Translated Amino Acid Sequences from 17 Recent Human Isolates of Orientia

Inter- and Intra-Operator Variability in the Reading of Indirect Immunofluorescence Assays for the Serological Diagnosis of Scrub Typhus and Murine Typhus

Evaluation of a rapid colorimetric field test to assess the effective life of long-lasting insecticide-treated mosquito nets in the Lao PDR

63 Scrub Typhus

Eight novel hepatitis C virus genomes reveal the changing taxonomic structure of genotype 6

Healthcare Providers and Population's Knowledge Regarding the Risks Related to Medicinal Products Use: A Cross-Sectional Study in Laos.

Prognostic indicators in adults hospitalized with falciparum malaria in Western Thailand.

Complete genome of a genotype I Japanese encephalitis virus isolated from a patient with encephalitis in Vientiane, Lao PDR

Multi-platform technologies for the integral characterization of poor-quality medicines

Evaluation of a Simple Blood Culture Amplification and Antigen Detection Method for Diagnosis of Salmonella enterica Serovar Typhi Bacteremia

Building bridges between law enforcement and public health communities to combat pharmaceutical crime

Causes of fever - hoof beats are rarely from zebras

63 Scrub Typhus

Use of the Correlation Coefficient to Compare a Point-of-Care Antigen Test Against a Quantitative Sandwich Enzyme-Linked Immunosorbent Assay for the Detection of Cryptococcal Meningitis

Coagulation and inflammation in scrub typhus and murine typhus—a prospective comparative study from Laos

How to achieve international action on falsified and substandard medicines

Optimal sampling designs for accurate estimation of parasite clearance in the context of artemisinin resistance

Defining disease heterogeneity to guide the empirical treatment of febrile illness in resource poor settings

Evaluation of the Standard Diagnostics Leptospira IgM ELISA for diagnosis of acute leptospirosis in Lao PDR

Comparison of Performance of Serum and Plasma in Panbio Dengue and Japanese Encephalitis Virus Enzyme-Linked Immunosorbent Assays

A Prospective Assessment of the Accuracy of Commercial IgM ELISAs in Diagnosis of Japanese Encephalitis Virus Infections in Patients with Suspected Central Nervous System Infections in Laos

Poor-quality antimalarial drugs in southeast Asia and sub-Saharan Africa

High hospital incidence of Staphylococcus aureus bacteremia in young infants in the Lao PDR

The WWARN Antimalarial Quality Surveyor

Burkholderia pseudomallei Detection in Surface Water in Southern Laos Using Moore's Swabs

Interview.

A Major Genome Region Underlying Artemisinin Resistance in Malaria

No Evidence for Spread of Plasmodium falciparum Artemisinin Resistance to Savannakhet Province, Southern Laos

Orientia tsutsugamushi in Human Scrub Typhus Eschars Shows Tropism for Dendritic Cells and Monocytes Rather than Endothelium

Multiple independent introductions of Plasmodium falciparum in South America

Mapping the aetiology of non-malarial febrile illness in Southeast Asia through a systematic review--terra incognita impairing treatment policies.

Actinomycetoma in SE Asia: the first case from Laos and a review of the literature.

Efficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern Laos.

Bartonella and Rickettsia in arthropods from the Lao PDR and from Borneo, Malaysia

Characteristics of CTX-M ESBL-producing Escherichia coli isolates from the Lao People's Democratic Republic, 2004-09.

The primacy of public health considerations in defining poor quality medicines.

A review of parasitic zoonoses in a changing Southeast Asia.

Poor quality drugs : grand challenges in high throughput detection, countrywide sampling, and forensics in developing countries

Urine Antibiotic Activity in Patients Presenting to Hospitals in Laos: Implications for Worsening Antibiotic Resistance

Bowel obstruction from wild bananas: a neglected health problem in Laos

Erythrocyte transketolase activity, markers of cardiac dysfunction and the diagnosis of infantile beriberi

Clinically unapparent infantile thiamin deficiency in Vientiane, Laos

In Response

Randomized Soil Survey of the Distribution of Burkholderia pseudomallei in Rice Fields in Laos

Poor quality vital anti-malarials in Africa - an urgent neglected public health priority.

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.

Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey.

Chromoblastomycosis after a leech bite complicated by myiasis: a case report.

Predictive diagnostic value of the tourniquet test for the diagnosis of dengue infection in adults

Bartonella and Rickettsia in arthropods from the Lao PDR and from Borneo, Malaysia

A review of parasitic zoonoses in a changing Southeast Asia

Untitled Response

Contrasting Spatial Distribution and Risk Factors for Past Infection with Scrub Typhus and Murine Typhus in Vientiane City, Lao PDR

A Phase III, Randomized, Non-Inferiority Trial to Assess the Efficacy and Safety of Dihydroartemisinin-Piperaquine in Comparison with Artesunate-Mefloquine in Patients with Uncomplicated Plasmodium falciparum Malaria in Southern Laos

Correction: An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia

Enhanced Determination of Streptococcus pneumoniae Serotypes Associated with Invasive Disease in Laos by Using a Real-Time Polymerase Chain Reaction Serotyping Assay with Cerebrospinal Fluid

Accuracy of Rapid IgM-Based Immunochromatographic and Immunoblot Assays for Diagnosis of Acute Scrub Typhus and Murine Typhus Infections in Laos

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia

The infective causes of hepatitis and jaundice amongst hospitalised patients in Vientiane, Laos

Intrinsic fluoroquinolone resistance in Orientia tsutsugamushi

Impact of poor-quality medicines in the ‘developing’ world

Diagnosis of Scrub Typhus

In Vivo Parasitological Measures of Artemisinin Susceptibility

Accuracy of AccessBio Immunoglobulin M and Total Antibody Rapid Immunochromatographic Assays for the Diagnosis of Acute Scrub Typhus Infection▿ †

Chapter 122 Scrub typhus and other tropical rickettsioses

Counterfeit and Substandard Anti-infectives in Developing Countries

Antimalarial drug quality: methods to detect suspect drugs

Chapter 122 Scrub typhus and other tropical rickettsioses

Sennetsu neorickettsiosis: a probable fish-borne cause of fever rediscovered in Laos.

Comparison of indirect immunofluorescence assays for diagnosis of scrub typhus and murine typhus using venous blood and finger prick filter paper blood spots.

Guidelines for field surveys of the quality of medicines: a proposal.

Postpartum traditions and nutrition practices among urban Lao women and their infants in Vientiane, Lao PDR

N-acetylcysteine as adjunctive treatment in severe malaria: A randomized, double-blinded placebo-controlled clinical trial*

Genetic history of hepatitis C virus in East Asia.

Postpartum traditions and nutrition practices among urban Lao women and their infants in Vientiane, Lao PDR (vol 63, pg 323, 2009)

A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR - implications for therapeutic failure and drug resistance.

Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis.

Fatal Chromobacterium violaceum septicaemia in northern Laos, a modified oxidase test and post-mortem forensic family G6PD analysis.

A phenomenon useful for the detection of Salmonella implementing a device from citrus extracts

Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis

Molecular detection of Bartonella species in rodents from the Lao PDR

Different Clinical Expression of Murine Typhus and Scrub Typhus

Simple, rapid and sensitive detection of Orientia tsutsugamushi by loop-isothermal DNA amplification

Detecting counterfeit antimalarial tablets by near-infrared spectroscopy

Characterization of "Yaa Chud" Medicine on the Thailand-Myanmar border: selecting for drug-resistant malaria and threatening public health.

Adaptive copy number evolution in malaria parasites.

Genotyping of Orientia tsutsugamushi from Humans with Scrub Typhus, Laos - Volume 14, Number 9—September 2008 - Emerging Infectious Diseases journal - CDC

Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry

Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar.

Differential patterns of endothelial and leucocyte activation in ‘typhus-like’ illnesses in Laos and Thailand

Impaired clinical response in a patient with uncomplicated falciparum malaria who received poor-quality and underdosed intramuscular artemether.

Noma in Laos: stigma of severe poverty in rural Asia.

Real-time multiplex PCR assay for detection and differentiation of rickettsiae and orientiae

Prevalence and Detection of Counterfeit Pharmaceuticals: A Mini Review

A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia.

Evaluation of the Panbio dengue virus nonstructural 1 antigen detection and immunoglobulin M antibody enzyme-linked immunosorbent assays for the diagnosis of acute dengue infections in Laos.

Fatal bacteremia due to immotile Vibrio cholerae serogroup O21 in Vientiane, Laos - a case report

The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria.

A major trichinellosis outbreak suggesting a high endemicity of trichinella infection in northern Laos

Public health impact of establishing the cause of bacterial infections in rural Asia.

ADAPTIVE COPY NUMBER EVOLUTION OF A KEY GENE IN THE FOLATE PATHWAY OF MALARIA PARASITES

Adaptive copy number evolution in malaria parasites

Simple, rapid and sensitive detection of Orientia tsutsugamushi by loop-isothermal DNA amplification

The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria

Antimicrobial Drug Resistance of Salmonella enterica Serovar Typhi in Asia and Molecular Mechanism of Reduced Susceptibility to the Fluoroquinolones

Accuracy of Burkholderia pseudomallei Identification Using the API 20NE System and a Latex Agglutination Test

Characterization of genuine and fake artesunate anti-malarial tablets using Fourier transform infrared imaging and spatially offset Raman spectroscopy through blister packs

Toad poisoning in Laos.

Prospective Study To Determine Accuracy of Rapid Serological Assays for Diagnosis of Acute Dengue Virus Infection in Laos▿

Letters to the editors

Correction: The Global Threat of Counterfeit Drugs: Why Industry and Governments Must Communicate the Dangers

Factors associated with a measles outbreak in children admitted at Mahosot Hospital, Vientiane, Laos

Contrasting genetic structure in Plasmodium vivax populations from Asia and South America

Combined molecular and clinical assessment of Plasmodium falciparum antimalarial drug resistance in the Lao People's Democratic Republic (Laos).

Diagnosis and management of malaria by rural community health providers in the Lao People's Democratic Republic (Laos)

Obstructive biliary ascariasis with cholangitis and hepatic abscesses in Laos: A case report with gall bladder ultrasound video

Corrigendum to “Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality” [J. Pharm. Biomed. Anal. 43 (2007) 105–110]

Counterfeit artemisinin derivatives and Africa: update from authors.

Prevalence of hepatitis E virus antibodies in pigs: implications for human infections in village-based subsistence pig farming in the Lao PDR

Thiamin deficiency and uncomplicated falciparum malaria in Laos

Reactive Desorption Electrospray Ionization Linear Ion Trap Mass Spectrometry of Latest-Generation Counterfeit Antimalarials via Noncovalent Complex Formation

Acquired haemophilia A in early pregnancy associated with Plasmodium vivax malaria and hyperthyroidism.

In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).

Fast detection and identification of counterfeit antimalarial tablets by Raman spectroscopy

Combined Fourier-transform infrared imaging and desorption electrospray-ionization linear ion-trap mass spectrometry for analysis of counterfeit antimalarial tablets

Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality

Untitled

Differential patterns of endothelial activation in 'typhus-like' illness

Analysis of HCV in South East Asia

Counterfeit and substandard antimalarial drugs

The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.

A trichinellosis outbreak in Borikhamxay Province, Lao PDR

Causes of community-acquired bacteremia and patterns of antimicrobial resistance in Vientiane, Laos.

A simple and inexpensive container for the transport of biological specimens in limited resource situations

Characterization of counterfeit artesunate antimalarial tablets from southeast Asia.

Limited Diagnostic Capacities of Two Commercial Assays for the Detection of Leptospira Immunoglobulin M Antibodies in Laos

Counterfeit anti-infective drugs

An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin–piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos)

A systematic review and meta-analysis of the diagnostic accuracy of rapid immunochromatographic assays for the detection of dengue virus IgM antibodies during acute infection

Characterization of Solid Counterfeit Drug Samples by Desorption Electrospray Ionization and Direct‐analysis‐in‐real‐time Coupled to Time‐of‐flight Mass Spectrometry

Manslaughter by fake artesunate in Asia - will Africa be next?

The Comparative Accuracy of 8 Commercial Rapid Immunochromatographic Assays for the Diagnosis of Acute Dengue Virus Infection

Rickettsial infections and fever, Vientiane, Laos.

Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations

Erratum: Manslaughter by fake artesunate in Asia - Will Africa be next? (PLoS Medicine 3,6 DOI: 10.1371/journal.pmed.0030197)

Misattribution of Central Nervous System Dysfunction to Artesunate

Geographical Distribution of Selected and Putatively Neutral SNPs in Southeast Asian Malaria Parasites

Misattribution of Central Nervous System Dysfunction to Artesunate

Correction: Estimation of the Total Parasite Biomass in Acute Falciparum Malaria from Plasma PfHRP2

Two Randomized Controlled Trials of Ceftazidime Alone versus Ceftazidime in Combination with Trimethoprim-Sulfamethoxazole for the Treatment of Severe Melioidosis

Open-Label Randomized Trial of Oral Trimethoprim-Sulfamethoxazole, Doxycycline, and Chloramphenicol Compared with Trimethoprim-Sulfamethoxazole and Doxycycline for Maintenance Therapy of Melioidosis

Sporotrichosis, Plain of Jars, Lao People's Democratic Republic - Volume 11, Number 9—September 2005 - Emerging Infectious Diseases journal - CDC

Selection strength and hitchhiking around two anti-malarial resistance genes

A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos.

Pharmacokinetics of Oral Doxycycline during Combination Treatment of Severe Falciparum Malaria

The global threat of counterfeit drugs: why industry and governments must communicate the dangers.

Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2

Use of a refractometer to assess the quality of antimalarial drugs collected in the Lao Pdr

Rickettsial infections are common causes of fever amongst adults in the Lao PDR

Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross‐sectional survey on the prevalence of fake antimalarials

Randomized Comparison of Chloroquine plus Sulfadoxine-Pyrimethamine versus Artesunate plus Mefloquine versus Artemether-Lumefantrine in the Treatment of Uncomplicated Falciparum Malaria in the Lao People's Democratic Republic

Platelets and Blood Coagulation in Human Malaria

Mixed-species malaria infections in humans

In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand.

Platelet-Induced Autoagglutination of Plasmodium falciparum-Infected Red Blood Cells and Disease Severity in Thailand

Short Communication: An assessment of the use of malaria rapid tests by village health volunteers in rural Laos

Treatment response in Lao children with P-FalcimparumMalaria

Platelet-induced autoagglutination of Plasmodium falciparum-infected red blood cells and disease severity in Thailand

Artemether bioavailability after oral or intramuscular administration in uncomplicated falciparum malaria.

Chloroquine versus Sulfadoxine-Pyrimethamine for Treatment of Plasmodium falciparum Malaria in Savannakhet Province, Lao People's Democratic Republic: An Assessment of National Antimalarial Drug Recommendations

Dietary and socio-economic factors associated with beriberi in breastfed Lao infants

A Selective Sweep Driven by Pyrimethamine Treatment in Southeast Asian Malaria Parasites

Dietary and socio-economic factors associated with beriberi in breastfed Lao infants

Counterfeit artesunate antimalarials in southeast Asia

Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria.

A randomized comparison of oral chloroquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in Laos

Diabetes Mellitus, Insulin, and Melioidosis in Thailand

Pneumocystis carinii pneumonia with pleurisy, platypnoea and orthodeoxia

Malaria and amphetamine ‘horse tablets’ in Thailand

A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis.

Retinal haemorrhage in P falciparum malaria.

Central Role of the Spleen in Malaria Parasite Clearance

Murder by fake drugs

Comparison of Oral Artesunate and Dihydroartemisinin Antimalarial Bioavailabilities in Acute Falciparum Malaria

Central role of the spleen in malaria parasite clearance

Bird notes from the Siang River Valley, Arunachal Pradesh, India

Contribution of humoral immunity to the therapeutic response in falciparum malaria.

A comparison of oral artesunate and artemether antimalarial bioactivities in acute falciparum malaria

Contribution of humoral immunity to the therapeutic response in falciparum malaria.

A comparison of artesunate alone with combined artesunate and quinine in the parenteral treatment of acute falciparum malaria

Erratum: Fake artesunate in southeast Asia (Lancet (1949))

A comparison of the in vivo kinetics of Plasmodium falciparum ring–infected erythrocyte surface antigen–positive and –negative erythrocytes

Fake artesunate in southeast Asia

Oral quinine pharmacokinetics and dietary salt intake

Melioidosis and Pandora's Box in the Lao People's Democratic Republic

Oral quinine pharmacokinetics and dietary salt intake

Melioidosis and Pandora's box in the Lao People's Democratic Republic

Antimalarial Bioavailability and Disposition of Artesunate in Acute Falciparum Malaria

Parasite Multiplication Potential and the Severity of Falciparum Malaria

Parasite multiplication potential and the severity of Falciparum malaria

Leptospirosis

Alcoholic Ketoacidosis as the Cause of Repeated Episodes of Severe Metabolic Acidosis

Pharmacokinetics of quinine and 3-hydroxyquinine in severe falciparum malaria with acute renal failure

Salmonella enteritidis and Acute Renal Failure

Hypothyroid nails and evolution

Psittacosis associated with bilateral 4th cranial nerve palsies

For creationists, a call to the bar

Social stability and change among forest hanuman langurs (Presbytis entellus)

Colobine monkeys society

Can animals teach us medicine?

Feeding and ranging patterns of forest hanuman langurs (Presbytis entellus)

The use of medicinal plants by primates: A missing link?

Possible buccal administration of herbal drugs by wild chimpanzees, Pan troglodytes

Foetal arm prolapse and presumed maternal death in a wild hanuman langur (Presbytis entellus)

A collection of small mammals from eastern Nepal

Foetal arm prolapse and presumed maternal death in a wild hanuman langur

Associations between Langur Monkeys (Presbytis entellus) and Chital Deer (Axis axis): Chance Encounters or a Mutualism?

The structure and phenology of a moist deciduous forest in the Central Indian Highlands

The variable social organization of hanuman langurs(Presbytis entellus), infanticide, and the monopolization of females

Dung and dung beetles in Kanha Tiger Reserve, central Indian highlands

The social organization of forest hanuman langurs(Presbytis entellus)

INFANTICIDE IN AN UNDISTURBED FOREST POPULATION OF HANUMAN LANGURS, PRESBYTIS-ENTELLUS

The birds of Kanha Tiger Reserve, Madhya Pradesh, India

Leapfrogging in cattle egrets (Bubulcus ibis).

Use of self-tindering Cordia firesaws by the Baiga of the Maikal Hills.

A note on golden jackals (Canis aureus) and their relationship with langurs (Presbytis entellus) in Kanha Tiger Reserve

INFANTICIDE AND SOCIAL-CHANGE IN FOREST GREY LANGURS, PRESBYTIS-ENTELLUS, IN KANHA TIGER RESERVE, INDIA

A feeding association between a heteropteran bug and langurs.

BIOLOGY UNDER THE RAJ

The first record of a rare murine rodent Diomys and further records of three shew species from Nepal

Predicting Salmonella Typhi incidence using prevalence metrics from sentinel studies of community-onset bloodstream infections

The highly diverse and complex plasmid population found in Escherichia coli colonising travellers to Laos and their role in antimicrobial resistance gene carriage

Predicting Salmonella Typhi incidence using prevalence metrics from sentinel studies of community-onset bloodstream infections

Falsified Medicine - April Fakes Day

A Case-Control Study of the Causes of Acute Respiratory Infection among Hospitalized Patients in Northeastern Laos

Complete genomes of Rickettsia typhi reveal a clonal population

A novel framework for quantifying the clinical impact of substandard and falsified antimicrobials: application to typhoid fever.

Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines

Predicting Salmonella Typhi incidence using prevalence metrics from sentinel studies of community-onset bloodstream infections: a secondary analysis of observational data

Simple and rapid low-cost assays to investigate ethylene glycol and diethylene glycol contamination in raw materials and medicinal syrups

The Medicine Quality Monitoring Globe: A public health intelligence system for collecting and curating reports of substandard and falsified medical products from publicly available Internet news media

Professor Paul Newton

BIOGRAPHY

Key Publications

Publications