Tuesday, 15 October 2019
Artists explore the problems of poor quality and fake medicines
When we are ill, we trust that the medicines that we take will make us feel and be better. But what if our pills do not contain the ingredients listed on the packaging? The art exhibition ‘What’s in your medicines?’ explores how substandard and falsified (‘fake’) medicines can affect our health, by ...
Wednesday, 9 October 2019
Meet the Chagas Scientific Advisory Committee
The first meeting of the newly formed Chagas Scientific Advisory Committee (SAC) recently took place to shape the key aims and objectives of the Chagas disease data sharing platform. The platform was recently launched by the Infectious Diseases Data Observatory (IDDO) in collaboration with the Drugs...
Friday, 4 October 2019
New research supports co-administration of primaquine with artemisinin-based combination therapies for P. vivax malaria
An individual patient data meta-analysis of 2,017 patients from 19 studies has found a high risk of recurrence following treatment of P. vivax malaria with artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) unless they are co-administered with primaquine. The research, published in...
Monday, 30 September 2019
Latest research explores new statistical approaches for estimating antimalarial drug efficacy
WWARN’s Clinical Scientific Group have published research in BMC Medical Research methodology and Malaria Journal comparing different statistical approaches for deriving cumulative estimates of drug efficacy from clinical studies. Results indicate that the Cumulative Incidence Function (CIF) approac...
Thursday, 15 August 2019
IDDO symposium to open BSP Spring Meeting
The British Society of Parasitology’s (BSP) three-day Spring Meeting is one of the biggest events in the society’s calendar and takes place at the University of Edinburgh from 15–17 April 2020. A strong malaria theme will run through the next meeting and IDDO is delighted to announce it will be open...
Wednesday, 7 August 2019
New Chagas collaboration to aggregate and standardise data
IDDO has launched a new global Chagas scientific collaboration with the Drugs for Neglected Diseases initiative (DNDi). The new platform will collate and standardise data to accelerate better treatments for the 6–7 million people worldwide with Chagas disease.
Thursday, 1 August 2019
Latest research finds primaquine improves haemoglobin by day 42 following treatment of P. vivax malaria
An IDDO/WWARN study has found that primaquine is not associated with increased levels of anaemia following treatment of patients without G6PD deficiency for P. vivax malaria and should be used as part of a radical cure. In the largest study of its kind to date, researchers carried out a systematic r...
Wednesday, 24 July 2019
Antimalarial treatments less effective in severely malnourished children
Researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment for uncomplicated falciparum malaria. The study, which is the first to specifically address this, has be...
Sunday, 7 July 2019
West African workshop
IDDO's WWARN hosted a successful workshop in West Africa aimed at improving researchers’ skills. The aim of the workshops was two-fold; to train researchers in best practice of designing, conducting, analysing and reporting antimalarial drug clinical trials, and also to build expertise within the...
Tuesday, 2 July 2019
Longer follow-up needed for malaria treatment in pregnant women
New research published in Open Forum Infectious Diseases has found that a longer follow-up is required to assess antimalarial drug efficacy in pregnant women. This was found across all drugs assessed in low malaria transmission settings. The report’s authors have called for guidelines specifically f...