Publications
Below is a list of research publications published in scientific journals by WWARN and our research partners. Use the filters to explore the publications by research theme or by using our list of key words. All links lead to PubMed.
If you cannot find a publication, please email info@wwarn.org.
Collaborative health and enforcement operations on the quality of antimalarials and antibiotics in southeast Asia.
Yong, Y., Plançon, A., Lau, Y., Hostetler, D., Fernández, F., Green, M., Sounvoravong, S., Nara, S., Boravann, M., Dumrong, T., Bangsawan, N., Low, M., Lim, C.-C., Ai, R., & Newton, P. (2015). The American Journal of Tropical Medicine and Hygiene, 92(6 Suppl), 105-112.
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Tun, K., Imwong, M., Lwin, K., Win, A., Hlaing, T., Hlaing, T., Lin, K., Kyaw, M., Plewes, K., Faiz, M., Dhorda, M., Cheah, P., Pukrittayakamee, S., Ashley, E., Anderson, T., Nair, S., McDew-White, M., Flegg, J., Grist, E., … Woodrow, C. (2015). The Lancet Infectious Diseases, 15(4), 415-421.
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
Takala-Harrison, S., Jacob, C., Arze, C., Cummings, M., Silva, J., Dondorp, A., Fukuda, M., Hien, T., Mayxay, M., Noedl, H., Nosten, F., Kyaw, M., Nhien, N., Imwong, M., Bethell, D., Se, Y., Lon, C., Tyner, S., Saunders, D., … Plowe, C. (2015). The Journal of Infectious Diseases, 211(5), 670-679.
Genetic architecture of artemisinin-resistant Plasmodium falciparum
Miotto, O., Amato, R., Ashley, E., MacInnis, B., Almagro-Garcia, J., Amaratunga, C., Lim, P., Mead, D., Oyola, S., Dhorda, M., Imwong, M., Woodrow, C., Manske, M., Stalker, J., Drury, E., Campino, S., Amenga-Etego, L., Thanh, T.-N., Tran, H., … Kwiatkowski, D. (2015). Nature Genetics, 47(3), 226-234.
DEVELOPMENT OF ANTIBODY-BASED IMMUNO-ASSAYS FOR QUALITY CONTROL OF ARTEMISININ-BASED COMBINATION THERAPIES
Khalil, I., Ding, X., Gonzalez, I., Bygbjerg, I., Fernandez, F., Newton, P., Alifrangis, M., & Koch, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 455-455.
LARGE-SCALE SCANS FOR GENOMIC REGIONS UNDER POSITIVE SELECTION IN SOUTHEAST ASIAN PLASMODIUM FALCIPARUM REVEAL GENES OF PUBLIC HEALTH IMPORTANCE
Jacob, C., Arze, C., Saunders, D., Lanteri, C., Fairhurst, R., Amaratunga, C., Tan, J., Miller, B., Miotto, O., MacInnis, B., Lim, P., Suon, S., Yi, P., Sreng, S., Jittamala, P., Chotivanich, K., Imwong, M., Chutasmit, K., Suchatsoonthorn, C., … Plowe, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 560-560.
HUMORAL IMMUNITY CONTRIBUTES TO CLEARANCE OF ARTEMISININ-RESISTANT PARASITES IN SOUTHEAST ASIA
Travassos, M., Bailey, J., Takala-Harrison, S., Manwani, B., Berry, A., Pablo, J., Jasinskas, A., Nakajima, R., Adams, M., Ashley, E., Dhorda, M., Nosten, F., Phyo, A., Newton, P., Mayxay, M., Dondorp, A., Tran, T., Han, K.-T., Kway, M., … Plowe, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 289-289.
Mapping fever aetiologies in malaria-endemic areas: an interactive, open-access, on-line map
Hopkins, H., Thomas, N., Crump, J., Gonzalez, I., Guerin, P., Newton, P., Schellenberg, D., Bell, D., & Reyburn, H. (2015). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 20, 179-179.
Prototype positive control wells for malaria rapid diagnostic tests: training effectiveness, impact on RDT use and health worker perceptions in Lao PDR and Uganda
Kyabayinze, D., Hopkins, H., Mayxay, M., Phommasone, K., Streat, E., Bwanika, J., Umlauf, R., Kibira, S., Ndawula, B., Gonzalez, I., Newton, P., Bell, D., & Cunningham, J. (2015). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 20, 181-181.
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Ashley, E., Aweeka, F., Barnes, K., Bassat, Q., Borrmann, S., Dahal, P., Davis, T., Deloron, P., Denis, M., Djimde, A., Faucher, J., Genton, B., Guérin, P., Hamed, K., Hodel, E., Huang, L., Jullien, V., Karunajeewa, H., Kiechel, … Workman, L. (2015). BMC Medicine, 13(1).
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data
Abdulla, S., Adam, I., Adjei, G., Adjuik, M., Alemayehu, B., Allan, R., Arinaitwe, E., Ashley, E., Barennes, H., Barnes, K., Bassat, Q., Baudin, E., Berens-Riha, N., Bjoerkman, A., Bompart, F., Bonnet, M., Borrmann, S., Bousema, T., Brasseur, P., … Gonzalez, R. (2015). BMC Medicine, 13(1).
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis
Abdulla, S., Ashley, E., Bassat, Q., Bethell, D., Bjorkman, A., Borrmann, S., D’Alessandro, U., Dahal, P., Day, N., Diakite, M., Djimde, A., Dondorp, A., Duong, S., Edstein, Fairhurst, R., Faiz, M., Falade, C., Flegg, J., Fogg, C., … Winstanley, P. (2015). Malaria Journal, 14(1).
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data
Adjuik, M., Allan, R., Anvikar, A., Ashley, E., Barennes, H., Barnes, K., Bassat, Q., Baudin, E., Bjorkman, A., Bompart, F., Bonnet, M., Borrmann, S., Brasseur, P., Bukirwa, H., Checchi, F., Cot, M., Dahal, P., D’Alessandro, U., Deloron, P., … Ibrahim, L. (2015). BMC Medicine, 13(1).
Genomic epidemiology of the current wave of artemisinin resistant malaria
Amato, R., Miotto, O., Woodrow, C., Almagro-Garcia, J., Sinha, I., Campino, S., Mead, D., Drury, E., Kekre, M., Sanders, M., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Anderson, T., Andrianaranjaka, V., Apinjoh, T., Ashley, E., Auburn, S., Awandare, G., … MalariaGEN Plasmodium falciparum Community Project. (2015).
Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
Mok, S., Ashley, E., Ferreira, P., Zhu, L., Lin, Z., Yeo, T., Chotivanich, K., Imwong, M., Pukrittayakamee, S., Dhorda, M., Nguon, C., Lim, P., Amaratunga, C., Suon, S., Hien, T., Htut, Y., Faiz, M., Onyamboko, M., Mayxay, M., … Bozdech, Z. (2015). Science (New York, N.Y.), 347(6220), 431-435.
Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria.
White, N., Ashley, E., Recht, J., Delves, M., Ruecker, A., Smithuis, F., Eziefula, A., Bousema, T., Drakeley, C., Chotivanich, K., Imwong, M., Pukrittayakamee, S., Prachumsri, J., Chu, C., Andolina, C., Bancone, G., Hien, T., Mayxay, M., Taylor, W., … Nosten, F. (2014). Malaria Journal, 13(1), 483.
Artemisinin resistance--modelling the potential human and economic costs
Lubell, Y., Dondorp, A., Guérin, P., Drake, T., Meek, S., Ashley, E., Day, N., White, N., & White, L. (2014). Malaria Journal, 13(1), 452.
Population pharmacokinetics of quinine in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda.
Kloprogge, F., Jullien, V., Piola, P., Dhorda, M., Muwanga, S., Nosten, F., Day, N., White, N., Guerin, P., & Tarning, J. (2014). The Journal of Antimicrobial Chemotherapy, 69(11), 3033-3040.
Cost of treating inpatient falciparum malaria on the Thai-Myanmar border
Kyaw, S., Drake, T., Ruangveerayuth, R., Chierakul, W., White, N., Newton, P., & Lubell, Y. (2014). Malaria Journal, 13(1), 416.
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.
Venkatesan, M., Gadalla, N., Stepniewska, K., Dahal, P., Nsanzabana, C., Moriera, C., Price, R., Mårtensson, A., Rosenthal, P., Dorsey, G., Sutherland, C., Guérin, P., Davis, T., Ménard, D., Adam, I., Ademowo, G., Arze, C., Baliraine, F., Berens-Riha, N., … Ogutu, B. (2014). American Journal of Tropical Medicine and Hygiene, 91(4), 833-843.
Spread of artemisinin resistance in Plasmodium falciparum malaria.
Ashley, E., Dhorda, M., Fairhurst, R., Amaratunga, C., Lim, P., Suon, S., Sreng, S., Anderson, J., Mao, S., Sam, B., Sopha, C., Chuor, C., Nguon, C., Sovannaroth, S., Pukrittayakamee, S., Jittamala, P., Chotivanich, K., Chutasmit, K., Suchatsoonthorn, C., … Tracking Resistance to Artemisinin Collaboration (TRAC). (2014). The New England Journal of Medicine, 371(5), 411-423.
Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN).
Lourens, C., Lindegardh, N., Barnes, K., Guerin, P., Sibley, C., White, N., & Tarning, J. (2014). Antimicrobial Agents and Chemotherapy, 58(7), 3889-3894.
Thiamin supplementation does not reduce the frequency of adverse events after anti-malarial therapy among patients with falciparum malaria in southern Laos.
Mayxay, M., Khanthavong, M., Cox, L., Sichanthongthip, O., Imwong, M., Pongvongsa, T., Hongvanthong, B., Phompida, S., Vanisaveth, V., White, N., & Newton, P. (2014). Malaria Journal, 13, 275.
Mind the gaps - The epidemiology of poor-quality anti-malarials in the malarious world - Analysis of the WorldWide Antimalarial Resistance Network database
Tabernero, P., Fernández, F., Green, M., Guerin, P., & Newton, P. (2014). Malaria Journal, 13(1).
Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries
Tanomsing, N., Mayxay, M., Newton, P., Nosten, F., Dolecek, C., Hien, T., White, N., Day, N., Dondorp, A., & Imwong, M. (2014). PLoS ONE, 9(4), e93942.