Category
Dr
Prabin
Dahal
Head of Statistics
Email
Research Theme
Visceral leishmaniasis
Malaria
Chagas
Trachoma
WWARN
Prabin joined the WorldWide Antimalarial Research Network (WWARN) – the prototypic model to IDDO – as a statistician in September 2011. His work with WWARN included assessment of the relationship between weight-adjusted dose and parasitological outcomes for artemisinin combination therapies.
His doctoral thesis (2015–2018, Linacre College) explored different statistical approaches for handling parasitic recurrences when quantifying antimalarial blood stage efficacy in P. falciparum.
In his current role, Prabin's main focus is the quantification of risk of severe and serious adverse events following antileishmanial therapies. His interest lies in exploring methodological issues in design and analysis of antileishmanial clinical trials.
Research Theme: VL, Malaria, Non-Malarial Febrile Illness
All Publications
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Ashley, E., Aweeka, F., Barnes, K., Bassat, Q., Borrmann, S., Dahal, P., Davis, T., Deloron, P., Denis, M., Djimde, A., Faucher, J., Genton, B., Guérin, P., Hamed, K., Hodel, E., Huang, L., Jullien, V., Karunajeewa, H., Kiechel, … Workman, L. (2015). BMC Medicine, 13(1).
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data
Adjuik, M., Allan, R., Anvikar, A., Ashley, E., Barennes, H., Barnes, K., Bassat, Q., Baudin, E., Bjorkman, A., Bompart, F., Bonnet, M., Borrmann, S., Brasseur, P., Bukirwa, H., Checchi, F., Cot, M., Dahal, P., D’Alessandro, U., Deloron, P., … Ibrahim, L. (2015). BMC Medicine, 13(1).
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.
Venkatesan, M., Gadalla, N., Stepniewska, K., Dahal, P., Nsanzabana, C., Moriera, C., Price, R., Mårtensson, A., Rosenthal, P., Dorsey, G., Sutherland, C., Guérin, P., Davis, T., Ménard, D., Adam, I., Ademowo, G., Arze, C., Baliraine, F., Berens-Riha, N., … Ogutu, B. (2014). American Journal of Tropical Medicine and Hygiene, 91(4), 833-843.
Clinical determinants of early parasitological response after ACT treatment in patients diagnosed with uncomplicated malaria in Africa: a pooled analysis of individual patient data
Dahal, P. (2014). Malaria Journal, 13(Suppl 1), P24 - P24.
The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data
Achan, J., Adam, I., Arinaitwe, E., Ashley, E., Awab, G., Barnes, K., Bassat, Q., Borrmann, S., Bousema, T., Dahal, P., D’Alessandro, U., Davis, T., Dondorp, A., Dorsey, G., Drakeley, C., Fanello, C., Faye, B., Flegg, J., Gaye, O., … Phyo, A. (2013). PLOS MEDICINE, 10(12), 1-17.
The power of pooled analysis to inform optimal dosing strategies for Artemisinin Combination Therapies (ACTs)
Guerin, P., Moreira, C., Dahal, P., Piola, P., Stepniewska, K., & Price, R. (2012). Malaria Journal, 11(Suppl 1), P40 - P40.
The prognostic utility of soluble fms‐like tyrosine kinase-1 (sFlt-1) and placental growth factor (PlGF) biomarkers for predicting preeclampsia: A secondary analysis of data from the INSPIRE trial
Kifle, M., Dahal, P., Vatish, M., Cerdeira, A., & Ohuma, E. (n.d.). In Authorea.
Assessing the impact of testing for COVID-19 using lateral flow devices in NHS acute trusts in England
Chen, S., Hounsell, R., Cantrell, L., Tsui, L., Naidoo, R., Dahal, P., Creswell, R., Bajaj, S., Flegg, J., Fowler, T., Hopkins, S., Lambert, B., Voysey, M., White, L., Consortium, E.-O., Stepniewska, K., & Shretta, R. (n.d.). In medRxiv.
Assessment of a combined strategy of seasonal malaria chemoprevention and supplementation with Vitamin A, Zinc and Plumpy’DozTM to prevent malaria and malnutrition in children under five years old in Burkina Faso: a randomized open label trial (SMC-NUT)
Sondo, P., TAHITA, M., ROUAMBA, T., DERRA, K., KABORE, B., COMPAORE, C., OUEDRAOGO, F., ROUAMBA, E., ILBOUDO, H., BAMBARA, E., NANA, M., SAWADOGO, E., SORGHO, H., SOME, A., VALEA, I., DAHAL, P., TRAORE/COULIBALY, M., & TINTO, H. (n.d.). In Research Square.
Infectious Diseases Data Observatory (IDDO) Visceral Leishmaniasis Library of Clinical Therapeutic Studies: A Protocol for a Living Systematic Review of Clinical Studies
Singh-Phulgenda, S., Rashan, S., Harriss, E., Dahal, P., Naylor, C., Brack, M., Guerin, P., & Maguire, B. (n.d.). In Research Square.
Prognostic Models Predicting Clinical Outcomes in Patients Diagnosed with Visceral Leishmaniasis: A Systematic Review
Wilson, J., Chowdhury, F., Hassan, S., Harriss, E., Alves, F., Musa, A., Dahal, P., Stepniewska, K., & Guérin, P. (n.d.). In medRxiv.