Category
Professor
Paul
Newton
Head of Medicine Quality Research Group
Email
Research Theme
Medicine quality
Professor Paul Newton is Head of the IDDO Medicine Quality Research Group. He was appointed Head of the WorldWide Antimalarial Research Network (WWARN) Antimalarial Quality Group in 2010. He was the founding Director of the Lao-Oxford-Mahosot-Wellcome Trust Research Unit (LOMWRU) in the Microbiology Laboratory of Mahosot Hospital in Vientiane, Laos, from 2000 to 2019 and now works based from Oxford. After junior doctor training in infectious disease and internal medicine in the UK, he worked in the Mahidol Oxford Research Unit in Bangkok on malaria and melioidosis for four years before moving to Laos.
All Publications
Innovative method for rapid detection of falsified COVID-19 vaccines through unopened vials using handheld Spatially Offset Raman Spectroscopy (SORS)
Mosca, S., Lin, Q., Stokes, R., Bharucha, T., Gangadharan, B., Clarke, R., Gomez Fernandez, L., Deats, M., Walsby-tickle, J., Yohan Arman, B., Chunekar, S., Patil, K., Gairola, S., Van Assche, K., Dunachie, S., Merchant, H., Kuwana, R., Maes, A., McCullagh, J., … Matousek, P. (2023). Vaccine, 41(47), 6960-6968.
The uncertain role of substandard and falsified medicines in the emergence and spread of antimicrobial resistance
Cavany, S., Nanyonga, S., Hauk, C., Lim, C., Tarning, J., Sartorius, B., Dolecek, C., Caillet, C., Newton, P., & Cooper, B. (2023). Nature Communications, 14(1).
Longitudinal comparison of bacterial pathogen seropositivity among wet
market vendors in the Lao People's Democratic Republic
Senvanpan, N., Phimolsarnnousith, V., Rattanavong, S., Mayxay, M., Reinharz, D., Fine, A., Horwood, P., Dussart, P., Blacksell, S., Pruvot, M., Newton, P., & Robinson, M. (2023). One Health, 17.
Is this pill an antibiotic or a painkiller? Improving the identification of oral antibiotics for better use
Monnier, A., Do, N., Asante, K., Afari-Asiedu, S., Khan, W., Munguambe, K., Sevene, E., Tran, T., Nguyen, C., Punpuing, S., Gómez-Olivé, F., van Doorn, H., Caillet, C., Newton, P., Ariana, P., & Wertheim, H. (2023). Lancet Global Health, 11(8), e1308 - e1313.
Estimating the prevalence of poor-quality anti-TB medicines: a neglected risk for global TB control and resistance
Tabernero, P., & Newton, P. (2023). BMJ Global Health, 8(7).
Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection
Bharucha, T., Gangadharan, B., Kumar, A., Myall, A., Ayhan, N., Pastorino, B., Chanthongthip, A., Vongsouvath, M., Mayxay, M., Sengvilaipaseuth, O., Phonemixay, O., Rattanavong, S., O’brien, D., Vendrell, I., Fischer, R., Kessler, B., Turtle, L., de Lamballerie, X., Dubot-Peres, A., … Zitzmann, N. (2023). Journal of Proteome Research, 22(6), 1614-1629.
The highly diverse plasmid population found in Escherichia coli colonizing travellers to Laos and its role in antimicrobial resistance gene carriage
Snaith, A., Dunn, S., Moran, R., Newton, P., Dance, D., Davong, V., Kuenzli, E., Kantele, A., Corander, J., & McNally, A. (2023). Microbial Genomics, 9(5).
The quality of antiretroviral medicines: an uncertain problem
Do, N., Boupha, P., Newton, P., & Caillet, C. (2023). BMJ Global Health, 8(3).
Intravenous doxycycline, azithromycin, or both for severe scrub typhus
Varghese, G., Dayanand, D., Gunasekaran, K., Kundu, D., Wyawahare, M., Sharma, N., Chaudhry, D., Mahajan, S., Saravu, K., Aruldhas, B., Mathew, B., Nair, R., Newbigging, N., Mathew, A., Abhilash, K., Biswal, M., Prasad, A., Zachariah, A., Iyadurai, R., … Day, N. (2023). New England Journal of Medicine, 388(9), 792-803.
Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples
MalariaGEN, Abdel Hamid, M., Abdelraheem, M., Acheampong, D., Ahouidi, A., Ali, M., Almagro-Garcia, J., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Andagalu, B., Anderson, T., Andrianaranjaka, V., Aniebo, I., Aninagyei, E., Ansah, F., Ansah, P., Apinjoh, T., Arnaldo, P., … Dolecek, C. (2023). Wellcome Open Research, 8, 22-22.
Bartonella species in Cambodia, Ghana, Laos, and Peru: results from vector and sero-surveys
Mullins, K., Canal, E., Ouch, P., Tagoe, J., Attram, N., Yeboah, C., Kumordjie, S., Fox, A., Letizia, A., Rachlin, A., Nguyen, H., Robinson, M., Vongsouvath, M., Davong, V., Mayxay, M., Simons, M., Caranci, A., Newton, P., Richards, A., & Farris, C. (2023). Vector-Borne and Zoonotic Diseases, 23(1), 9-17.
Medical Products Quality and Public Health
Newton, P., & Caillet, C. (2023). In Manson’s Tropical Diseases, Fourth Edition (pp. 43-48).
The epidemiology of substandard and falsified vaccines and innovation for their detection in supply chains
Newton, P. (2023). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 28, 79-79.
Environmental DNA as an innovative technique to identify the origins of falsified antimalarial tablets-a pilot study of the pharmabiome
Young, J., Liddicoat, C., van Dijk, K.-J., Tabernero, P., Caillet, C., White, N., Linacre, A., Austin, J., & Newton, P. (2022). Scientific Reports, 12(1), 21997.
A robust host-response-based signature distinguishes bacterial and viral infections across diverse global populations
Rao, A., Popper, S., Gupta, S., Davong, V., Vaidya, K., Chanthongthip, A., Dittrich, S., Robinson, M., Vongsouvath, M., Mayxay, M., Nawtaisong, P., Karmacharya, B., Thair, S., Bogoch, I., Sweeney, T., Newton, P., Andrews, J., Relman, D., & Khatri, P. (2022). Cell Reports Medicine, 3(12).
Ten-year persistence and evolution of Plasmodium falciparum antifolate and anti-sulfonamide resistance markers pfdhfr and pfdhps in three Asian countries
Srisutham, S., Madmanee, W., Kouhathong, J., Sutawong, K., Tripura, R., Peto, T., van der Pluijm, R., Callery, J., Dysoley, L., Mayxay, M., Newton, P., Pongvongsa, T., Hongvanthong, B., Day, N., White, N., Dondorp, A., & Imwong, M. (2022). PLoS ONE, 17(12), e0278928.
Malaria outbreak in Laos driven by a selective sweep for Plasmodium falciparum kelch13 R539T mutants: a genetic epidemiology analysis
Wasakul, V., Disratthakit, A., Mayxay, M., Chindavongsa, K., Sengsavath, V., Thuy-Nhien, N., Pearson, R., Phalivong, S., Xayvanghang, S., Maude, R., Gonçalves, S., Day, N., Newton, P., Ashley, E., Kwiatkowski, D., Dondorp, A., & Miotto, O. (2022). Lancet Infectious Diseases, 23(5), 568-577.
Orientia tsutsugamushi in chiggers and small mammals in Laos
Elliott, I., Kumlert, R., Thangnimitchok, N., Blacksell, S., Tanganuchitcharnchai, A., Paris, D., Newton, P., & Morand, S. (2022). Vector-Borne and Zoonotic Diseases, 22(10), 505-511.
Renewed risk for epidemic typhus related to war and massive population displacement, Ukraine
Newton, P., Fournier, P.-E., Tappe, D., & Richards, A. (2022). Emerging Infectious Diseases, 28(10), 2125-2126.
Substandard and falsified antibiotics: neglected drivers of antimicrobial resistance?
Zabala, G., Bellingham, K., Vidhamaly, V., Boupha, P., Boutsamay, K., Newton, P., & Caillet, C. (2022). BMJ Global Health, 7(8).
The quality of veterinary medicines and their implications for One Health
Vidhamaly, V., Bellingham, K., Newton, P., & Caillet, C. (2022). BMJ Global Health, 7(8).
Antimicrobial resistance patterns in bacteria causing febrile illness in Africa, South Asia, and Southeast Asia: a systematic review of published etiological studies from 1980-2015
Roberts, T., Dahal, P., Shrestha, P., Schilling, W., Shrestha, R., Ngu, R., Huong, V., van Doorn, H., Phimolsarnnousith, V., Miliya, T., Crump, J., Bell, D., Newton, P., Dittrich, S., Hopkins, H., Stepniewska, K., Guerin, P., Ashley, E., & Turner, P. (2022). International Journal of Infectious Diseases, 122.
Evaluation of trends in hospital antimicrobial use in the Lao PDR using repeated point-prevalence surveys-evidence to improve treatment guideline use
Chansamouth, V., Chommanam, D., Roberts, T., Keomany, S., Paphasiri, V., Phamisith, C., Sengsavang, S., Detleuxay, K., Phoutsavath, P., Bouthavong, S., Douangnouvong, A., Vongsouvath, M., Rattana, S., Keohavong, B., Day, N., Turner, P., van Doorn, H., Mayxay, M., Ashley, E., & Newton, P. (2022). The Lancet Regional Health - Western Pacific, 27.
Childhood encephalitis in the Greater Mekong region (the SouthEast Asia Encephalitis Project): a multicentre prospective study
Pommier, J., Gorman, C., Crabol, Y., Bleakley, K., Sothy, H., Santy, K., Tran, H., Nguyen, L., Bunnakea, E., Hlaing, C., Aye, A., Cappelle, J., Herrant, M., Piola, P., Rosset, B., Chevalier, V., Tarantola, A., Channa, M., Honnorat, J., … Lecuit, M. (2022). The Lancet Global Health, 10(7), e989 - e1002.
Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia
The, H., Bodhidatta, L., Pham, D., Mason, C., Thanh, T., Vinh, P., Turner, P., Hem, S., Dance, D., Newton, P., Phetsouvanh, R., Davong, V., Thwaites, G., Thomson, N., Baker, S., & Rabaa, M. (2022). Access Microbiology, 4(5).