Tuesday, 27 April 2021
ANTICOV: largest clinical trial in Africa for people with mild COVID-19 to test new drug combination
27 APRIL 2021 – The ANTICOV clinical trial, conducted in 13 African countries, has started the recruitment of participants to test a new drug combination, nitazoxanide + ciclesonide, to treat people with mild-to-moderate COVID-19 before their cases become severe.
Monday, 29 March 2021
Risks of serious adverse events following treatment for visceral leishmaniasis
The results of a large-scale systematic review and meta-analysis have published in PLOS Neglected Tropical Diseases. This research aimed to collate all reported serious adverse events (SAE) in visceral leishmaniasis (VL) clinical trials and quantify the incidence of mortality during the first 30 day...
Monday, 29 March 2021
Calls for clarity on pooled evidence in COVID-19 therapeutic reviews and guidelines
IDDO’s Director, Professor Philippe Guérin, has co-authored a letter published in The Lancet drawing attention of the risk of pooling data from uncomplicated illness and more severe ill hospitalised patients in the development of COVID-19 treatment guidelines. Although SARS-CoV-2 is one virus, the C...
Thursday, 18 March 2021
Researchers call for access to Ivermectin for young children
Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication. The WorldWide Antimalarial Resistance Network (WWARN)’s new meta-analysis published today provides evi...
Wednesday, 17 March 2021
Gender imbalance in visceral leishmaniasis clinical trials
Researchers have found that despite an ongoing trend for a decreasing proportion of males being enrolled in antileishmanial therapeutic efficacy trials over time, there are still 1.8 times as many males as females involved in clinical trials. A new systematic review and meta-analysis published today...
Tuesday, 16 March 2021
New report highlights growing concern of vaccine falsification
The Medicine Quality Research Group has published a new Medical Product Quality Report focussing on increasing issues around substandard and falsified (SF) COVID-19 vaccines. With the implementation of the key innovations of COVID-19 vaccines, there have been growing numbers of reports of SF vaccine...
Friday, 26 February 2021
Applications for RSTMH 2021 grants open
The small grants programme offers early career researchers and global health professionals based anywhere in the world the opportunity to apply for funding in a topic related to tropical medicine and global health. The programme funds projects across the research spectrum, including lab-based, clini...
Friday, 12 February 2021
Evidence supports WHO recommendation for PQ combined with ACTs to block Plasmodium falciparum transmission
Evidence from a new study, initiated by the Primaquine Roll Out Group and conducted at WWARN, supports the World Health Organization (WHO) recommendation for use of 0.25mg/kg dose of primaquine (PQ) combined with artemisinin-based combination therapies (ACT) to block Plasmodium falciparum transmissi...
Thursday, 4 February 2021
Geneva Health Forum panel on the elimination of NTDs and the new WHO Roadmap
The WHO 2030 NTD Roadmap has just been launched and a recent Geneva Health Forum panel took that as its starting point to discuss the possibility of eliminating neglected tropical diseases (NTDs). IDDO’s Director, Professor Philippe Guérin joined co-panellists Dr Amy Fall, the Global Health Medi...
Wednesday, 13 January 2021
Check-list recommended to improve reporting of microscopy methods and results in malaria studies
A study to explore the variations of how microscopy methods are reported in published malaria studies has recommended standardised procedures should be implemented for methodological consistency and comparability of clinical trial outcomes.
Wednesday, 2 December 2020
Tribute to the Memory of Prof. P. Claver Kayumba, University of Rwanda
It is with great sadness that IDDO has learnt of the death of Professor P. Claver Kayumba, who latterly coordinated academic and professional education programs at the EAC Regional Center of Excellence for Vaccines, Immunization and Health Supply Chain Management (RCE-VIHSCM), hosted by the Universi...
Friday, 27 November 2020
New study on the risk of Plasmodium vivax parasitaemia after Plasmodium falciparum malaria
A new study quantifying the high risk of Plasmodium vivax parasitaemia after treatment of Plasmodium falciparum malaria and exploring the factors associated with this has been published in PLOS Medicine.
Tuesday, 24 November 2020
Largest clinical trial in Africa to treat COVID-19 cases before they become severe is launched in 13 countries
NAIROBI/KINSHASA/GENEVA – Thirteen African countries and an international network of research institutions have joined forces to launch the largest COVID-19 clinical trial in mild-to-moderate outpatients in Africa. The ANTICOV clinical trial aims to respond to the urgent need to identify treatments ...
Monday, 26 October 2020
IDDO and ISARIC partner to support data collection and analysis for COVID-19
In January 2020, ISARIC (the International Severe Acute Respiratory and emerging Infections Consortium) launched an international initiative for standardised COVID-19 clinical data collection. Over the past nine months, there has been extensive global participation, resulting in one of the world’s l...
Monday, 19 October 2020
New Clinical Data Report from ISARIC
The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) is producing a weekly report using clinical data from its COVID-19 database. To date, this includes data from 122,361 individuals from 578 sites across 42 countries.
Monday, 21 September 2020
BMC publishes series of IDDO papers about the causes of non-malarial febrile illnesses globally
A series of articles that set out to explore the global distribution of infections that cause non-malarial febrile illness (NMFI) has today been published in BMC Medicine.The series brings together the results of large-scale systematic reviews of the causes of fever in Africa, Latin America, and Sou...
Monday, 14 September 2020
Professor Paul Newton wins the Helen Clark-JoPPP Award
We are delighted to announce that Professor Paul Newton has won the Helen-Clark-JoPPP Award for Pharmaceutical Policy and Practice Research. Professor Newton has been presented with the award based on the scientific merit of his work, as well as its impact on patients, decisions makers, and on g...
Thursday, 10 September 2020
Microscopy standards to harmonise methods for malaria clinical research studies
Research Malaria Microscopy Standards (ReMMS) applicable to malaria clinical research studies have been published in Malaria Journal. The paper describes the rationale for proposed standards to prepare, stain and examine blood films for malaria parasites.