Wednesday, 24 July 2019
Antimalarial treatments less effective in severely malnourished children
Researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment for uncomplicated falciparum malaria. The study, which is the first to specifically address this, has be...
Sunday, 7 July 2019
West African workshop
IDDO's WWARN hosted a successful workshop in West Africa aimed at improving researchers’ skills. The aim of the workshops was two-fold; to train researchers in best practice of designing, conducting, analysing and reporting antimalarial drug clinical trials, and also to build expertise within the...
Tuesday, 2 July 2019
Longer follow-up needed for malaria treatment in pregnant women
New research published in Open Forum Infectious Diseases has found that a longer follow-up is required to assess antimalarial drug efficacy in pregnant women. This was found across all drugs assessed in low malaria transmission settings. The report’s authors have called for guidelines specifically f...
Wednesday, 22 May 2019
IDDO gets behind the Santa Cruz Letter for action on Chagas
A letter signed by IDDO, members of the Chagas Platform and the Chagas Global Coalition calling on governments, organisations and donors to intensify efforts to control and eliminate Chagas has been presented to the World Health Organization (WHO).
Saturday, 18 May 2019
Latest research explores new statistical approaches for estimating antimalarial drug efficacy
IDDO and WWARN's Clinical Scientific Group have published research in BMC Medical Research Methodology comparing different statistical approaches for deriving cumulative estimates of drug efficacy from clinical studies. Results indicate that the Cumulative Incidence Function (CIF) approach should be...
Monday, 13 May 2019
New Data Access Committee begins work on Ebola
The Ebola Data Platform, a pioneering collaboration in Ebola and emerging infections, has today appointed nine members for its first Data Access Committee (DAC), overseen and chaired by TDR, the Special Programme for Research and Training in Tropical Diseases, hosted at WHO.
Monday, 13 May 2019
Le nouveau Comité d'accès aux données commence ses travaux sur Ebola
La plateforme de données Ebola, une collaboration pionnière dans le domaine d'Ebola et des infections émergentes, a nommé aujourd'hui neuf membres à son premier Comité d'accès aux données (CAD), supervisé et présidé par le TDR, le Programme spécial de recherche et de formation sur les maladies tropi...
Thursday, 18 April 2019
World Malaria Day seminar 2019 – Antimalarial treatments for vulnerable groups
Professor Joel Tarning, Head of Clinical Pharmacology at MORU, and Head WWARN’s Pharmacometrics Group will present highlights on population PK/PD modelling to assess the dosing of antimalarial drugs in vulnerable groups. Dr Makoto Saito will share highlights from his research on antimalarial treatme...
Wednesday, 3 April 2019
Malaria DREAM Challenge on drug resistance: open for pre-registration
Malaria is still a global health burden, despite numerous coordinated efforts for eradication. One obstacle to eradication is the malaria parasite’s quick adaptation to anti-malarial drugs resulting in drug resistance. Resistance mechanisms are ill understood for many antimalarials, making it diffic...
Friday, 29 March 2019
Grand Challenges Africa launch Ki Data Challenge to improve maternal and child health
A Ki Data Challenge has been launched by Grand Challenges Africa (GCA) - a programme of the African Academy of Sciences (AAS) supported through the AAS funding and programmes implementation platform, the Alliance for Accelerating Excellence in Science in Africa (AESA) - and the African Academy of Sc...
Friday, 22 March 2019
Tackling resistance with triple ACTs? Encouraging results in Southeast Asia
Rob van der Pluijm presents findings from the Tracking Resistance to Artemesinin Collaboration II programme, which looks at the further extension of drug resistant malaria in Southeast Asia, and the innovative analyses of Triple artemisinin combination therapies (TACTs). Latest news of the launch pl...