Professor
Philippe
Guérin
Ebola SC Member
Oxford University
After working as a physician in France and Nepal, Philippe joined Médecins Sans Frontières where he gained extensive experience of working in the field and as a researcher working on malaria and tuberculosis. He spent six years as the Scientific Director of Epicentre in Paris, a World Health Organization Collaborating Centre for Research in Epidemiology and Response to Emerging Diseases. Prior to this, he spent three years as a senior advisor at the Norwegian Institute of Public Health.
Philippe is Director of the Infectious Diseases Data Observatory (IDDO), which collates and pools clinical, laboratory and epidemiological data on select poverty-related diseases and emerging infections. IDDO is building upon the success of the WorldWide Antimalarial Resistance Network (WWARN), a scientifically independent, multi-disciplinary platform, founded in 2009 to provide the information necessary to prevent or alleviate antimalarial drug resistance and therefore reduce malaria morbidity and mortality.
All Publications
Febrile illness mapping-much of the world without data and without evidence-based treatments
Newton, P., & Guerin, P. (2020). BMC Medicine, 18(1).
Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980–2015
Elven, J., Dahal, P., Ashley, E., Thomas, N., Shrestha, P., Stepniewska, K., Crump, J., Newton, P., Bell, D., Reyburn, H., Hopkins, H., & Guerin, P. (2020). BMC Medicine, 18.
Towards harmonization of microscopy methods for malaria clinical research studies
Dhorda, M., Ba, E., Kevin Baird, J., Barnwell, J., Bell, D., Carter, J., Dondorp, A., Ekawati, L., Gatton, M., González, I., Guérin, P., Incardona, S., Lilley, K., Menard, D., Nosten, F., Obare, P., Ogutu, B., Olliaro, P., Price, R., … Sokhna, C. (2020). Malaria Journal, 19(1).
Efficacy of single dose primaquine with artemisinin combination therapy on P. falciparum gametocytes and transmission: A WWARN individual patient meta-analysis
Stepniewska, K., Humphreys, G., Gonçalves, B., Craig, E., Gosling, R., Guerin, P., Price, R., Barnes, K., Raman, J., Smit, M., D’Alessandro, U., Stone, W., Bjorkman, A., Samuels, A., Arroyo-Arroyo, M., Bastiaens, G., Brown, J., Dicko, A., El-Sayed, B., … Bousema, T. (2020). Journal of Infectious Diseases, 225(7), 1215-1226.
Drug treatments for covid-19: living systematic review and network meta-analysis.
Siemieniuk, R., Bartoszko, J., Ge, L., Zeraatkar, D., Izcovich, A., Kum, E., Pardo-Hernandez, H., Qasim, A., Martinez, J., Rochwerg, B., Lamontagne, F., Han, M., Liu, Q., Agarwal, A., Agoritsas, T., Chu, D., Couban, R., Cusano, E., Darzi, A., … Brignardello-Petersen, R. (2020). BMJ (Clinical Research Ed.), 370, m2980 - m2980.
Baseline results of a living systematic review for COVID-19 clinical trial registrations
Maguire, B., McLean, A., Rashan, S., Antonio, E., Bagaria, J., Bentounsi, Z., Brack, M., Caldwell, F., Carrara, V., Citarella, B., Dahal, P., Feteh, V., Guérin, M., Kennon, K., Bilton Lahaut, K., Makuka, G., Ngu, R., Obiesie, S., Richmond, C., … Guérin, P. (2020). Wellcome Open Research, 5.
Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Saito, M., Mansoor, R., Kennon, K., Anvikar, A., Ashley, E., Chandramohan, D., Cohee, L., D’Alessandro, U., Genton, B., Gilder, M., Juma, E., Kalilani-Phiri, L., Kuepfer, I., Laufer, M., Lwin, K., Meshnick, S., Mosha, D., Muehlenbachs, A., Mwapasa, V., … Guérin, P. (2020). BMC Medicine, 18(1).
The worldwide antimalarial resistance network clinical trials publication library: A live, open-access database of plasmodium treatment efficacy trials
Takata, J., Sondo, P., Humphreys, G., Burrow, R., Maguire, B., Hossain, M., Das, D., Commons, R., Price, R., & Guerin, P. (2020). American Journal of Tropical Medicine and Hygiene.
COVID-19 and risks to the supply and quality of tests, drugs, and vaccines
Newton, P., Bond, K., & 53 signatories from 20 countries. (2020). Lancet Global Health .
A living systematic review protocol for COVID-19 clinical trial registrations
Maguire, B., & Guerin, P. (2020). Wellcome Open Research, 5.
The consequence of COVID-19 on the global supply of medical products: Why Indian generics matter for the world?
Guerin, P., Singh-Phulgenda, S., & Strub-Wourgaft, N. (2020). F1000Research.
The consequence of COVID-19 on the global supply of medical products: Why Indian generics matter for the world?
Guerin, P., Singh-Phulgenda, S., & Strub-Wourgaft, N. (2020). F1000Research, 9.
Precision global health: a roadmap for augmented action
Sheath, D., de Castañeda, R., Bempong, N.-E., Raviglione, M., Machalaba, C., Pepper, M., Vayena, E., Ray, N., Wernli, D., Escher, G., Grey, F., Elger, B., Helbing, D., Kleineberg, K.-K., Beran, D., Miranda, J., Huffman, M., Hersch, F., Andayi, F., … Flahault, A. (2020). Journal of Public Health and Emergency, 4, 5-5.
The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: a meta-analysis of individual patient data
Bretscher, M., Dahal, P., Griffin, J., Stepniewska, K., Bassat, Q., Baudin, E., D’Alessandro, U., Djimde, A., Dorsey, G., Espié, E., Fofana, B., González, R., Juma, E., Karema, C., Lasry, E., Lell, B., Lima, N., Menéndez, C., Mombo-Ngoma, G., … Okell, L. (2020). BMC Medicine, 18(1).
Microbiology Investigation Criteria for Reporting Objectively (MICRO): A framework for the reporting and interpretation of clinical microbiology data
Turner, P., Fox-Lewis, A., Shrestha, P., Dance, D., Wangrangsimakul, T., Cusack, T.-P., Ling, C., Hopkins, J., Roberts, T., Limmathurotsakul, D., Cooper, B., Dunachie, S., Moore, C., Dolecek, C., van Doorn, H., Guerin, P., Day, N., & Ashley, E. (2020). Pathology, 52, s57.
In emergencies, health research must go beyond public engagement toward a true partnership with those affected
Wright, K., Parker, M., & Nuffield Council on Bioethics Working Group. (2020). Nature Medicine, 26(3), 308-309.
Baseline results of a living systematic review for COVID-19 clinical trial registrations.
Maguire, B., McLean, A., Rashan, S., Antonio, E., Bagaria, J., Bentounsi, Z., Brack, M., Caldwell, F., Carrara, V., Citarella, B., Dahal, P., Feteh, V., H B Guérin, M., Kennon, K., Bilton Lahaut, K., Makuka, G., Ngu, R., Obiesie, S., Richmond, C., … Guérin, P. (2020). Wellcome Open Research, 5, 116.
Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting
Dahal, P., Stepniewska, K., Guerin, P., D’Alessandro, U., Price, R., & Simpson, J. (2019). BMC Medical Research Methodology, 19.
Efficacy and tolerability of artemisinin- and quenine-based treatments for uncomplicated falciparum malaria during pregnanc: A WWARN individual patient data meta-analysis
Saito, M., Mansoor, R., Kennon, K., Anvikar, A., Ashley, E., Chandramohan, D., Cohee, L., D’Alessandro, U., Genton, B., Juma, E., Kalilani-Phiri, L., Kuepfer, I., Laufer, M., Lwin, K., Meshnick, S., Mosha, D., Mwapasa, V., Mwebaza, N., Nambozi, M., … Guerin, P. (2019). American Journal of Tropical Medicine and Hygiene, 101(S5), 81.
The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: a systematic review and individual patient data meta-analysis
Commons, R., Simpson, J., Thriemer, K., Abreha, T., Adam, I., Anstey, N., Assefa, A., Awab, G., Baird, J., Barber, B., Chu, C., Dahal, P., Daher, A., Davis, T., Dondorp, A., Grigg, M., Humphreys, G., Hwang, J., Karunajeewa, H., … Price, R. (2019). PLOS Medicine, 16(10).
The wwarn clinical trials publication library: a systematically constructed database of plasmodium clinical efficacy trials
Takata, J., Sondo, P., Burrow, R., Maguire, B., Hossain, S., Das, D., Commons, R., Price, R., & Guerin, P. (2019). Transactions of The Royal Society of Tropical Medicine and Hygiene, 113(September 2019), S168 - S169.
Efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a protocol for systematic review and individual patient data (IPD) meta-analysis
Saito, M., Mansoor, R., Kennon, K., McGready, R., Nosten, F., Guérin, P., & Stepniewska, K. (2019). BMJ Open, 9(8).
The haematological consequences of plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Commons, R., Simpson, J., Thriemer, K., Chu, C., Douglas, N., Abreha, T., Alemu, S., Añez, A., Anstey, N., Aseffa, A., Assefa, A., Awab, G., Baird, K., Barber, B., Borghini-Fuhrer, I., D’Alessandro, U., Dahal, P., Daher, A., De Vries, P., … Guerin, P. (2019). BMC Medicine, 17.
Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether‐lumefantrine for uncomplicated malaria
Chotsiri, P., Denoeud-Ndam, L., Baudin, E., Guindo, O., Diawara, H., Attaher, O., Smit, M., Guerin, P., Doumbo, O., Wiesner, L., Barnes, K., Hoglund, R., Dicko, A., Etard, J.-F., & Tarning, J. (2019). Clinical Pharmacology and Therapeutics, 106, 1299-1309.
A pooled analysis of the duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine
Bretscher, M., Dahal, P., Griffin, J., Stepniewska, K., Bassat, Q., Baudin, E., D’Alessandro, U., Djimde, A., Dorsey, G., Espie, E., Fofana, B., Gonzalez, R., Juma, E., Karema, C., Lasry, E., Lell, B., Lima, N., Menendez, C., Mombo-Ngoma, G., … Okell, L. (2019).