Professor
Philippe
Guérin
Membre - Comité de pilotage sur le virus Ebola (Ebola SC)
L'Université d’Oxford
Après avoir travaillé comme médecin en France et au Népal, Philippe a rejoint Médecins Sans Frontières où il a acquis une vaste expérience en tant que chercheur travaillant sur le terrain et sur le paludisme et la tuberculose. Il a été pendant six ans directeur scientifique d'Epicentre à Paris, un centre collaborateur de l'Organisation mondiale de la santé pour la recherche en épidémiologie et la réponse aux maladies émergentes. Auparavant, il a été conseiller principal à l'Institut norvégien de santé publique pendant trois ans.
Philippe est directeur de l'Observatoire de données sur les maladies infectieuses (IDDO), dont la mission est de rassembler et d'agréger des données cliniques, laboratoire et épidémiologiques sur certaines maladies sélectionnées liées à la pauvreté et sur les infections émergentes. IDDO s’appuie sur le succès du réseau WWARN (WorldWide Antimalarial Resistance Network), une plateforme scientifiquement indépendante et multidisciplinaire, créée en 2009 pour fournir les informations nécessaires pour empêcher ou alléger la résistance aux médicaments antipaludiques et de cette manière réduire la mortalité, et la morbidité du paludisme.
All Publications
Febrile illness mapping-much of the world without data and without evidence-based treatments
Newton, P., & Guerin, P. (2020). BMC Medicine, 18(1).
Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980–2015
Elven, J., Dahal, P., Ashley, E., Thomas, N., Shrestha, P., Stepniewska, K., Crump, J., Newton, P., Bell, D., Reyburn, H., Hopkins, H., & Guerin, P. (2020). BMC Medicine, 18.
Towards harmonization of microscopy methods for malaria clinical research studies
Dhorda, M., Ba, E., Kevin Baird, J., Barnwell, J., Bell, D., Carter, J., Dondorp, A., Ekawati, L., Gatton, M., González, I., Guérin, P., Incardona, S., Lilley, K., Menard, D., Nosten, F., Obare, P., Ogutu, B., Olliaro, P., Price, R., … Sokhna, C. (2020). Malaria Journal, 19(1).
Efficacy of single dose primaquine with artemisinin combination therapy on P. falciparum gametocytes and transmission: A WWARN individual patient meta-analysis
Stepniewska, K., Humphreys, G., Gonçalves, B., Craig, E., Gosling, R., Guerin, P., Price, R., Barnes, K., Raman, J., Smit, M., D’Alessandro, U., Stone, W., Bjorkman, A., Samuels, A., Arroyo-Arroyo, M., Bastiaens, G., Brown, J., Dicko, A., El-Sayed, B., … Bousema, T. (2020). Journal of Infectious Diseases, 225(7), 1215-1226.
Drug treatments for covid-19: living systematic review and network meta-analysis.
Siemieniuk, R., Bartoszko, J., Ge, L., Zeraatkar, D., Izcovich, A., Kum, E., Pardo-Hernandez, H., Qasim, A., Martinez, J., Rochwerg, B., Lamontagne, F., Han, M., Liu, Q., Agarwal, A., Agoritsas, T., Chu, D., Couban, R., Cusano, E., Darzi, A., … Brignardello-Petersen, R. (2020). BMJ (Clinical Research Ed.), 370, m2980 - m2980.
Baseline results of a living systematic review for COVID-19 clinical trial registrations
Maguire, B., McLean, A., Rashan, S., Antonio, E., Bagaria, J., Bentounsi, Z., Brack, M., Caldwell, F., Carrara, V., Citarella, B., Dahal, P., Feteh, V., Guérin, M., Kennon, K., Bilton Lahaut, K., Makuka, G., Ngu, R., Obiesie, S., Richmond, C., … Guérin, P. (2020). Wellcome Open Research, 5.
Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Saito, M., Mansoor, R., Kennon, K., Anvikar, A., Ashley, E., Chandramohan, D., Cohee, L., D’Alessandro, U., Genton, B., Gilder, M., Juma, E., Kalilani-Phiri, L., Kuepfer, I., Laufer, M., Lwin, K., Meshnick, S., Mosha, D., Muehlenbachs, A., Mwapasa, V., … Guérin, P. (2020). BMC Medicine, 18(1).
The worldwide antimalarial resistance network clinical trials publication library: A live, open-access database of plasmodium treatment efficacy trials
Takata, J., Sondo, P., Humphreys, G., Burrow, R., Maguire, B., Hossain, M., Das, D., Commons, R., Price, R., & Guerin, P. (2020). American Journal of Tropical Medicine and Hygiene.
COVID-19 and risks to the supply and quality of tests, drugs, and vaccines
Newton, P., Bond, K., & 53 signatories from 20 countries. (2020). Lancet Global Health .
A living systematic review protocol for COVID-19 clinical trial registrations
Maguire, B., & Guerin, P. (2020). Wellcome Open Research, 5.
The consequence of COVID-19 on the global supply of medical products: Why Indian generics matter for the world?
Guerin, P., Singh-Phulgenda, S., & Strub-Wourgaft, N. (2020). F1000Research.
The consequence of COVID-19 on the global supply of medical products: Why Indian generics matter for the world?
Guerin, P., Singh-Phulgenda, S., & Strub-Wourgaft, N. (2020). F1000Research, 9.
Precision global health: a roadmap for augmented action
Sheath, D., de Castañeda, R., Bempong, N.-E., Raviglione, M., Machalaba, C., Pepper, M., Vayena, E., Ray, N., Wernli, D., Escher, G., Grey, F., Elger, B., Helbing, D., Kleineberg, K.-K., Beran, D., Miranda, J., Huffman, M., Hersch, F., Andayi, F., … Flahault, A. (2020). Journal of Public Health and Emergency, 4, 5-5.
The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: a meta-analysis of individual patient data
Bretscher, M., Dahal, P., Griffin, J., Stepniewska, K., Bassat, Q., Baudin, E., D’Alessandro, U., Djimde, A., Dorsey, G., Espié, E., Fofana, B., González, R., Juma, E., Karema, C., Lasry, E., Lell, B., Lima, N., Menéndez, C., Mombo-Ngoma, G., … Okell, L. (2020). BMC Medicine, 18(1).
Microbiology Investigation Criteria for Reporting Objectively (MICRO): A framework for the reporting and interpretation of clinical microbiology data
Turner, P., Fox-Lewis, A., Shrestha, P., Dance, D., Wangrangsimakul, T., Cusack, T.-P., Ling, C., Hopkins, J., Roberts, T., Limmathurotsakul, D., Cooper, B., Dunachie, S., Moore, C., Dolecek, C., van Doorn, H., Guerin, P., Day, N., & Ashley, E. (2020). Pathology, 52, s57.
In emergencies, health research must go beyond public engagement toward a true partnership with those affected
Wright, K., Parker, M., & Nuffield Council on Bioethics Working Group. (2020). Nature Medicine, 26(3), 308-309.
Baseline results of a living systematic review for COVID-19 clinical trial registrations.
Maguire, B., McLean, A., Rashan, S., Antonio, E., Bagaria, J., Bentounsi, Z., Brack, M., Caldwell, F., Carrara, V., Citarella, B., Dahal, P., Feteh, V., H B Guérin, M., Kennon, K., Bilton Lahaut, K., Makuka, G., Ngu, R., Obiesie, S., Richmond, C., … Guérin, P. (2020). Wellcome Open Research, 5, 116.
Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting
Dahal, P., Stepniewska, K., Guerin, P., D’Alessandro, U., Price, R., & Simpson, J. (2019). BMC Medical Research Methodology, 19.
Efficacy and tolerability of artemisinin- and quenine-based treatments for uncomplicated falciparum malaria during pregnanc: A WWARN individual patient data meta-analysis
Saito, M., Mansoor, R., Kennon, K., Anvikar, A., Ashley, E., Chandramohan, D., Cohee, L., D’Alessandro, U., Genton, B., Juma, E., Kalilani-Phiri, L., Kuepfer, I., Laufer, M., Lwin, K., Meshnick, S., Mosha, D., Mwapasa, V., Mwebaza, N., Nambozi, M., … Guerin, P. (2019). American Journal of Tropical Medicine and Hygiene, 101(S5), 81.
The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: a systematic review and individual patient data meta-analysis
Commons, R., Simpson, J., Thriemer, K., Abreha, T., Adam, I., Anstey, N., Assefa, A., Awab, G., Baird, J., Barber, B., Chu, C., Dahal, P., Daher, A., Davis, T., Dondorp, A., Grigg, M., Humphreys, G., Hwang, J., Karunajeewa, H., … Price, R. (2019). PLOS Medicine, 16(10).
The wwarn clinical trials publication library: a systematically constructed database of plasmodium clinical efficacy trials
Takata, J., Sondo, P., Burrow, R., Maguire, B., Hossain, S., Das, D., Commons, R., Price, R., & Guerin, P. (2019). Transactions of The Royal Society of Tropical Medicine and Hygiene, 113(September 2019), S168 - S169.
Efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a protocol for systematic review and individual patient data (IPD) meta-analysis
Saito, M., Mansoor, R., Kennon, K., McGready, R., Nosten, F., Guérin, P., & Stepniewska, K. (2019). BMJ Open, 9(8).
The haematological consequences of plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Commons, R., Simpson, J., Thriemer, K., Chu, C., Douglas, N., Abreha, T., Alemu, S., Añez, A., Anstey, N., Aseffa, A., Assefa, A., Awab, G., Baird, K., Barber, B., Borghini-Fuhrer, I., D’Alessandro, U., Dahal, P., Daher, A., De Vries, P., … Guerin, P. (2019). BMC Medicine, 17.
Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether‐lumefantrine for uncomplicated malaria
Chotsiri, P., Denoeud-Ndam, L., Baudin, E., Guindo, O., Diawara, H., Attaher, O., Smit, M., Guerin, P., Doumbo, O., Wiesner, L., Barnes, K., Hoglund, R., Dicko, A., Etard, J.-F., & Tarning, J. (2019). Clinical Pharmacology and Therapeutics, 106, 1299-1309.
A pooled analysis of the duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine
Bretscher, M., Dahal, P., Griffin, J., Stepniewska, K., Bassat, Q., Baudin, E., D’Alessandro, U., Djimde, A., Dorsey, G., Espie, E., Fofana, B., Gonzalez, R., Juma, E., Karema, C., Lasry, E., Lell, B., Lima, N., Menendez, C., Mombo-Ngoma, G., … Okell, L. (2019).