Collection of samples for mefloquine / carboxymefloquine pharmacology analysis

The purpose of this document is to standardise the sample collection procedure during clinical studies of mefloquine / carboxymefloquine antimalarial drugs. This should be considered as a recommendation/minimum requirements  for homogeneous quality in the pre-analytical study phase and to guide the collection, processing, preservation, storage, shipment and safe handling of samples from human origin.