Category
Professor
Paul
Newton
Head of Medicine Quality Research Group
Email
Research Theme
Medicine quality
Professor Paul Newton is Head of the IDDO Medicine Quality Research Group. He was appointed Head of the WorldWide Antimalarial Research Network (WWARN) Antimalarial Quality Group in 2010. He was the founding Director of the Lao-Oxford-Mahosot-Wellcome Trust Research Unit (LOMWRU) in the Microbiology Laboratory of Mahosot Hospital in Vientiane, Laos, from 2000 to 2019 and now works based from Oxford. After junior doctor training in infectious disease and internal medicine in the UK, he worked in the Mahidol Oxford Research Unit in Bangkok on malaria and melioidosis for four years before moving to Laos.
All Publications
Integration of novel low-cost colorimetric, laser photometric, and visual fluorescent techniques for rapid identification of falsified medicines in resource-poor areas: application to artemether-lumefantrine.
Green, M., Hostetler, D., Nettey, H., Swamidoss, I., Ranieri, N., & Newton, P. (2015). The American Journal of Tropical Medicine and Hygiene, 92(6 Suppl), 8-16.
Evaluation of molecular methods to improve the detection of Burkholderia pseudomallei in soil and water samples from Laos.
Knappik, M., Dance, D., Rattanavong, S., Pierret, A., Ribolzi, O., Davong, V., Silisouk, J., Vongsouvath, M., Newton, P., & Dittrich, S. (2015). Applied and Environmental Microbiology, 81(11), 3722-3727.
Estimated under-five deaths associated with poor-quality antimalarials in sub-Saharan Africa.
Renschler, J., Walters, K., Newton, P., & Laxminarayan, R. (2015). The American Journal of Tropical Medicine and Hygiene, 92(6 Suppl), 119-126.
Colonization with Enterobacteriaceae producing ESBLs in children attending pre-school childcare facilities in the Lao People's Democratic Republic.
Stoesser, N., Xayaheuang, S., Vongsouvath, M., Phommasone, K., Elliott, I., Del Ojo Elias, C., Crook, D., Newton, P., Buisson, Y., Lee, S., & Dance, D. (2015). Journal of Antimicrobial Chemotherapy, 70(6), 1893-1897.
A novel technique for detecting antibiotic-resistant typhoid from rapid diagnostic tests.
Nic Fhogartaigh, C., Dance, D., Davong, V., Tann, P., Phetsouvanh, R., Turner, P., Dittrich, S., & Newton, P. (2015). Journal of Clinical Microbiology, 53(5), 1758-1760.
Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A.
Parry, C., Thieu, N., Dolecek, C., Karkey, A., Gupta, R., Turner, P., Dance, D., Maude, R., Ha, V., Tran, C., Thi, P., Be, B., Phi, L., Ngoc, R., Ghose, A., Dongol, S., Campbell, J., Thanh, D., Thanh, T., … Baker, S. (2015). Antimicrobial Agents and Chemotherapy, 59(5), 2756-2764.
Antibiotic prescription behaviours in Lao People's Democratic Republic: a knowledge, attitude and practice survey.
Quet, F., Vlieghe, E., Leyer, C., Buisson, Y., Newton, P., Naphayvong, P., Keoluangkhot, V., Chomarat, M., Longuet, C., Steenkeste, N., & Jacobs, J. (2015). Bulletin of the World Health Organization, 93(4), 219-227.
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
Takala-Harrison, S., Jacob, C., Arze, C., Cummings, M., Silva, J., Dondorp, A., Fukuda, M., Hien, T., Mayxay, M., Noedl, H., Nosten, F., Kyaw, M., Nhien, N., Imwong, M., Bethell, D., Se, Y., Lon, C., Tyner, S., Saunders, D., … Plowe, C. (2015). The Journal of Infectious Diseases, 211(5), 670-679.
Quality assurance of drugs used in clinical trials: proposal for adapting guidelines
Newton, P., Schellenberg, D., Ashley, E., Ravinetto, R., Green, M., ter Kuile, F., Tabernero, P., White, N., & Guerin, P. (2015). BMJ, 350.
Orientia, rickettsia, and leptospira pathogens as causes of CNS infections in Laos: a prospective study
Dittrich, S., Rattanavong, S., Lee, S., Panyanivong, P., Craig, S., Tulsiani, S., Blacksell, S., Dance, D., Dubot-Pérès, A., Sengduangphachanh, A., Phoumin, P., Paris, D., & Newton, P. (2015). Lancet Global Health, 3(2), e104 - e112.
High prevalence of Tropheryma whipplei in Lao kindergarten children.
Keita, A., Dubot-Pérès, A., Phommasone, K., Sibounheuang, B., Vongsouvath, M., Mayxay, M., Raoult, D., Newton, P., & Fenollar, F. (2015). PLoS Neglected Tropical Diseases, 9(2), e0003538.
An expanded taxonomy of hepatitis C virus genotype 6: characterization of 22 new full-length viral genomes
Li, C., Barnes, E., Newton, P., Fu, Y., Vongsouvath, M., Klenerman, P., Okamoto, H., Abe, K., Pybus, O., & Lu, L. (2015). Virology, 476, 355-363.
Infective endocarditis in the Lao PDR: clinical characteristics and outcomes in a developing country.
Mirabel, M., Rattanavong, S., Frichitthavong, K., Chu, V., Kesone, P., Thongsith, P., Jouven, X., Fournier, P.-E., Dance, D., & Newton, P. (2015). International Journal of Cardiology, 180, 270-273.
Genetic architecture of artemisinin-resistant Plasmodium falciparum
Miotto, O., Amato, R., Ashley, E., MacInnis, B., Almagro-Garcia, J., Amaratunga, C., Lim, P., Mead, D., Oyola, S., Dhorda, M., Imwong, M., Woodrow, C., Manske, M., Stalker, J., Drury, E., Campino, S., Amenga-Etego, L., Thanh, T.-N., Tran, H., … Kwiatkowski, D. (2015). Nature Genetics, 47(3), 226-234.
DEVELOPMENT OF ANTIBODY-BASED IMMUNO-ASSAYS FOR QUALITY CONTROL OF ARTEMISININ-BASED COMBINATION THERAPIES
Khalil, I., Ding, X., Gonzalez, I., Bygbjerg, I., Fernandez, F., Newton, P., Alifrangis, M., & Koch, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 455-455.
HUMORAL IMMUNITY CONTRIBUTES TO CLEARANCE OF ARTEMISININ-RESISTANT PARASITES IN SOUTHEAST ASIA
Travassos, M., Bailey, J., Takala-Harrison, S., Manwani, B., Berry, A., Pablo, J., Jasinskas, A., Nakajima, R., Adams, M., Ashley, E., Dhorda, M., Nosten, F., Phyo, A., Newton, P., Mayxay, M., Dondorp, A., Tran, T., Han, K.-T., Kway, M., … Plowe, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 289-289.
LARGE-SCALE SCANS FOR GENOMIC REGIONS UNDER POSITIVE SELECTION IN SOUTHEAST ASIAN PLASMODIUM FALCIPARUM REVEAL GENES OF PUBLIC HEALTH IMPORTANCE
Jacob, C., Arze, C., Saunders, D., Lanteri, C., Fairhurst, R., Amaratunga, C., Tan, J., Miller, B., Miotto, O., MacInnis, B., Lim, P., Suon, S., Yi, P., Sreng, S., Jittamala, P., Chotivanich, K., Imwong, M., Chutasmit, K., Suchatsoonthorn, C., … Plowe, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 560-560.
PATHOGEN-SPECIFIC FEATURES OF THE HUMAN PERIPHERAL BLOOD TRANSCRIPTIONAL PROFILE IN PATIENTS WITH SCRUB TYPHUS AND MURINE TYPHUS
Popper, S., Davong, V., Castonguay-Vanier, J., Chanthongthip, A., Phommasone, K., Vongsouvath, M., Dull, P., Basnyat, B., Murdoch, D., Woods, C., Moore, C., Newton, P., & Relman, D. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 128-128.
Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos.
Paris, D., Stephan, F., Bulder, I., Wouters, D., van der Poll, T., Newton, P., Day, N., & Zeerleder, S. (2015). PLoS Neglected Tropical Diseases, 9(8), e0003990.
Melioidosis in Laos
Buisson, Y., Rattanavong, S., Keoluangkhot, V., Vongphayloth, K., Manivanh, L., Phetsouvanh, R., Pierret, A., Maeght, J.-L., Wuthiekanun, V., Newton, P., & Dance, D. (2015). In Socio-Ecological Dimensions of Infectious Diseases in Southeast Asia (pp. 89-104). Springer Nature.
Prototype positive control wells for malaria rapid diagnostic tests: training effectiveness, impact on RDT use and health worker perceptions in Lao PDR and Uganda
Kyabayinze, D., Hopkins, H., Mayxay, M., Phommasone, K., Streat, E., Bwanika, J., Umlauf, R., Kibira, S., Ndawula, B., Gonzalez, I., Newton, P., Bell, D., & Cunningham, J. (2015). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 20, 181-181.
Mapping fever aetiologies in malaria-endemic areas: an interactive, open-access, on-line map
Hopkins, H., Thomas, N., Crump, J., Gonzalez, I., Guerin, P., Newton, P., Schellenberg, D., Bell, D., & Reyburn, H. (2015). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 20, 179-179.
A 30-year-old Male Trader from China with Persistent Fever
Newton, P., Keoluangkhot, V., Mayxay, M., Green, M., & Fernández, F. (2015). In Clinical Cases in Tropical Medicine (pp. 168-170). Elsevier.
A 2-month-old Girl from Laos with Dyspnoea, Cyanosis and Irritability
Mayxay, M., Soukaloun, D., & Newton, P. (2015). In Clinical Cases in Tropical Medicine (pp. 185-187). Elsevier.
A 72-year-old Male Farmer from Laos with Extensive Skin Lesions on the Lower Leg
Slesak, G., Inthalad, S., & Newton, P. (2015). In Clinical Cases in Tropical Medicine (pp. 123-125). Elsevier.