Category

Professor
Paul
Newton
Head of Medicine Quality Research Group
Email
Research Theme
Medicine quality
Professor Paul Newton is Head of the IDDO Medicine Quality Research Group. He was appointed Head of the WorldWide Antimalarial Research Network (WWARN) Antimalarial Quality Group in 2010. He was the founding Director of the Lao-Oxford-Mahosot-Wellcome Trust Research Unit (LOMWRU) in the Microbiology Laboratory of Mahosot Hospital in Vientiane, Laos, from 2000 to 2019 and now works based from Oxford. After junior doctor training in infectious disease and internal medicine in the UK, he worked in the Mahidol Oxford Research Unit in Bangkok on malaria and melioidosis for four years before moving to Laos.
All Publications
Optimal sampling designs for accurate estimation of parasite clearance in the context of artemisinin resistance
Flegg, J., Guerin, P., Nosten, F., Dondorp, A., Fairhurst, R., Socheat, D., Borrmann, S., Björkman, A., Mårtensson, A., Mayxay, M., Newton, P., Bethell, D., Se, Y., Noedl, H., Djimde, A., White, N., & Stepniewska, K. (2012). Malaria Journal, 11(Suppl 1), P39 - P39.
Mapping the aetiology of non-malarial febrile illness in Southeast Asia through a systematic review--terra incognita impairing treatment policies.
Acestor, N., Cooksey, R., Newton, P., Menard, D., Guerin, P., Nakagawa, J., Christophel, E., Gonzalez, I., & Bell, D. (2012). PloS One, 7(9).
Actinomycetoma in SE Asia: the first case from Laos and a review of the literature.
Rattanavong, S., Vongthongchit, S., Bounphamala, K., Vongphakdy, P., Gubler, J., Mayxay, M., Phetsouvanh, R., Elliott, I., Logan, J., Hill, R., Newton, P., & Dance, D. (2012). BMC Infectious Diseases, 12(1), 349.
Efficacy of artemether-lumefantrine, the nationally-recommended artemisinin combination for the treatment of uncomplicated falciparum malaria, in southern Laos.
Mayxay, M., Khanthavong, M., Chanthongthip, O., Imwong, M., Pongvongsa, T., Hongvanthong, B., Phompida, S., Vanisaveth, V., White, N., & Newton, P. (2012). Malar J, 11(1).
Multiple independent introductions of Plasmodium falciparum in South America
Yalcindag, E., Elguero, E., Arnathau, C., Durand, P., Akiana, J., Anderson, T., Aubouy, A., Balloux, F., Besnard, P., Bogreau, H., Carnevale, P., D’Alessandro, U., Fontenille, D., Gamboa, D., Jombart, T., Le Mire, J., Leroy, E., Maestre, A., Mayxay, M., … Prugnolle, F. (2012). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(2), 511-516.
Characteristics of CTX-M ESBL-producing Escherichia coli isolates from the Lao People's Democratic Republic, 2004-09.
Stoesser, N., Crook, D., Moore, C., Phetsouvanh, R., Chansamouth, V., Newton, P., & Jones, N. (2012). Journal of Antimicrobial Chemotherapy, 67(1), 240-242.
The primacy of public health considerations in defining poor quality medicines.
Newton, P., Amin, A., Bird, C., Passmore, P., Dukes, G., Tomson, G., Simons, B., Bate, R., Guerin, P., & White, N. (2011). PLoS Medicine, 8(12).
A review of parasitic zoonoses in a changing Southeast Asia
Conlan, J., Sripa, B., Attwood, S., & Newton, P. (2011). Veterinary Parasitology, 182(1), 22-40.
A review of parasitic zoonoses in a changing Southeast Asia
Conlan, J., Sripa, B., Attwood, S., & Newton, P. (2011). Veterinary Parasitology, 182(1), 22-40.
Urine antibiotic activity in patients presenting to hospitals in Laos: implications for worsening antibiotic resistance.
Khennavong, M., Davone, V., Vongsouvath, M., Phetsouvanh, R., Silisouk, J., Rattana, O., Mayxay, M., Castonguay-Vanier, J., Moore, C., Strobel, M., & Newton, P. (2011). The American Journal of Tropical Medicine and Hygiene, 85(2), 295-302.
Bowel obstruction from wild bananas: a neglected health problem in Laos.
Slesak, G., Mounlaphome, K., Inthalad, S., Phoutsavath, O., Mayxay, M., & Newton, P. (2011). Tropical Doctor, 41(2), 85-90.
Erythrocyte transketolase activity, markers of cardiac dysfunction and the diagnosis of infantile beriberi
Soukaloun, D., Lee, S., Chamberlain, K., Taylor, A., Mayxay, M., Sisouk, K., Soumphonphakdy, B., Latsavong, K., Akkhavong, K., Phommachanh, D., Sengmeuang, V., Luangxay, K., McDonagh, T., White, N., & Newton, P. (2011). PLoS Neglected Tropical Diseases, 5(2), ARTN e971.
Clinically unapparent infantile thiamin deficiency in Vientiane, Laos
Khounnorath, S., Chamberlain, K., Taylor, A., Soukaloun, D., Mayxay, M., Lee, S., Phengdy, B., Luangxay, K., Sisouk, K., Soumphonphakdy, B., Latsavong, K., Akkhavong, K., White, N., & Newton, P. (2011). PLoS Neglected Tropical Diseases, 5(2), ARTN e969.
In Response
Peacock, S., & Newton, P. (2011). The American Society of Tropical Medicine and Hygiene, 84(2), 359-359.
Randomized soil survey of the distribution of Burkholderia pseudomallei in rice fields in Laos.
Rattanavong, S., Wuthiekanun, V., Langla, S., Amornchai, P., Sirisouk, J., Phetsouvanh, R., Moore, C., Peacock, S., Buisson, Y., & Newton, P. (2011). Applied and Environmental Microbiology, 77(2), 532-536.
Poor quality vital anti-malarials in Africa - an urgent neglected public health priority.
Newton, P., Mildenhall, D., Plançon, A., Nettey, H., Nyadong, L., Hostetler, D., Swamidoss, I., Harris, G., Powell, K., Timmermans, A., Amin, A., Opuni, S., Barbereau, S., Faurant, C., Soong, R., Faure, K., Thevanayagam, J., Fernandes, P., Kaur, H., … Fernández, F. (2011). Malaria Journal, 10(1), 352.
Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.
Mok, S., Imwong, M., Mackinnon, M., Sim, J., Ramadoss, R., Yi, P., Mayxay, M., Chotivanich, K., Liong, K., Russell, B., Socheat, D., Newton, P., Day, N., White, N., Preiser, P., Nosten, F., Dondorp, A., & Bozdech, Z. (2011). BMC Genomics, 12(1), 391.
Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey.
Lubell, Y., Staedke, S., Greenwood, B., Molyneux, M., Newton, P., Reyburn, H., Snow, R., D’Alessandro, U., English, M., Day, N., Kremsner, P., Dondorp, A., Mbacham, W., Dorsey, G., Owusu-Agyei, S., Maitland, K., Krishna, S., Newton, C., Pasvol, G., … Whitty, C. (2011). PloS One, 6(2).
Chromoblastomycosis after a leech bite complicated by myiasis: a case report.
Slesak, G., Inthalad, S., Strobel, M., Marschal, M., Hall, M., & Newton, P. (2011). BMC Infectious Diseases, 11(1).
Predictive diagnostic value of the tourniquet test for the diagnosis of dengue infection in adults.
Mayxay, M., Phetsouvanh, R., Moore, C., Chansamouth, V., Vongsouvath, M., Sisouphone, S., Vongphachanh, P., Thaojaikong, T., Thongpaseuth, S., Phongmany, S., Keolouangkhot, V., Strobel, M., & Newton, P. (2011). Trop Med Int Health, 16(1), 127-133.
Contrasting spatial distribution and risk factors for past infection with scrub typhus and murine typhus in Vientiane City, Lao PDR.
Vallée, J., Thaojaikong, T., Moore, C., Phetsouvanh, R., Richards, A., Souris, M., Fournet, F., Salem, G., Gonzalez, J.-P., & Newton, P. (2010). PLoS Neglected Tropical Diseases, 4(12), e909 - 1.
A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.
Mayxay, M., Keomany, S., Khanthavong, M., Souvannasing, P., Stepniewska, K., Khomthilath, T., Keola, S., Pongvongsa, T., Phompida, S., Ubben, D., Valecha, N., White, N., & Newton, P. (2010). Am J Trop Med Hyg, 83(6), 1221-1229.
Enhanced determination of Streptococcus pneumoniae serotypes associated with invasive disease in Laos by using a real-time polymerase chain reaction serotyping assay with cerebrospinal fluid.
Moore, C., Sengduangphachanh, A., Thaojaikong, T., Sirisouk, J., Foster, D., Phetsouvanh, R., McGee, L., Crook, D., Newton, P., & Peacock, S. (2010). Am J Trop Med Hyg, 83(3), 451-457.
Accuracy of rapid IgM-based immunochromatographic and immunoblot assays for diagnosis of acute scrub typhus and murine typhus infections in Laos.
Blacksell, S., Jenjaroen, K., Phetsouvanh, R., Tanganuchitcharnchai, A., Phouminh, P., Phongmany, S., Day, N., & Newton, P. (2010). The American Journal of Tropical Medicine and Hygiene, 83(2), 365-369.
An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia
Valecha, N., Phyo, A., Mayxay, M., Newton, P., Krudsood, S., Keomany, S., Khanthavong, M., Pongvongsa, T., Ruangveerayuth, R., Uthaisil, C., Ubben, D., Duparc, S., Bacchieri, A., Corsi, M., Rao, B., Bhattacharya, P., Dubhashi, N., Ghosh, S., Dev, V., … Pukrittayakamee, S. (2010). PloS One, 5(7), e11880.