Category
Professor
Paul
Newton
Head of Medicine Quality Research Group
Email
Research Theme
Medicine quality
Professor Paul Newton is Head of the IDDO Medicine Quality Research Group. He was appointed Head of the WorldWide Antimalarial Research Network (WWARN) Antimalarial Quality Group in 2010. He was the founding Director of the Lao-Oxford-Mahosot-Wellcome Trust Research Unit (LOMWRU) in the Microbiology Laboratory of Mahosot Hospital in Vientiane, Laos, from 2000 to 2019 and now works based from Oxford. After junior doctor training in infectious disease and internal medicine in the UK, he worked in the Mahidol Oxford Research Unit in Bangkok on malaria and melioidosis for four years before moving to Laos.
All Publications
A trichinellosis outbreak in Borikhamxay Province, Lao PDR.
Sayasone, S., Odermatt, P., Vongphrachanh, P., Keoluangkot, V., Dupouy-Camet, J., Newton, P., & Strobel, M. (2006). Transactions of the Royal Society of Tropical Medicine and Hygiene, 100(12), 1126-1129.
The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.
Newton, P., Barnes, K., Smith, P., Evans, A., Chierakul, W., Ruangveerayuth, R., & White, N. (2006). Eur J Clin Pharmacol, 62(12), 1003-1009.
A simple and inexpensive container for the transport of biological specimens in limited resource situations.
Blacksell, S., Khounsy, S., Phetsouvanh, R., & Newton, P. (2006). Transactions of the Royal Society of Tropical Medicine and Hygiene, 100(11), 1084-1086.
Causes of community-acquired bacteremia and patterns of antimicrobial resistance in Vientiane, Laos.
Phetsouvanh, R., Phongmany, S., Soukaloun, D., Rasachak, B., Soukhaseum, V., Soukhaseum, S., Frichithavong, K., Khounnorath, S., Pengdee, B., Phiasakha, K., Chu, V., Luangxay, K., Rattanavong, S., Sisouk, K., Keolouangkot, V., Mayxay, M., Ramsay, A., Blacksell, S., Campbell, J., … Newton, P. (2006). Am J Trop Med Hyg, 75(5), 978-985.
Characterization of counterfeit artesunate antimalarial tablets from southeast Asia.
Hall, K., Newton, P., Green, M., De Veij, M., Vandenabeele, P., Pizzanelli, D., Mayxay, M., Dondorp, A., & Fernandez, F. (2006). The American Journal of Tropical Medicine and Hygiene, 75(5), 804-811.
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos.
Blacksell, S., Smythe, L., Phetsouvanh, R., Dohnt, M., Hartskeerl, R., Symonds, M., Slack, A., Vongsouvath, M., Davong, V., Lattana, O., Phongmany, S., Keolouangkot, V., White, N., Day, N., & Newton, P. (2006). Clin Vaccine Immunol, 13(10), 1166-1169.
Counterfeit anti-infective drugs.
Newton, P., Green, M., Fernández, F., Day, N., & White, N. (2006). Lancet Infect Dis, 6(9), 602-613.
A systematic review and meta-analysis of the diagnostic accuracy of rapid immunochromatographic assays for the detection of dengue virus IgM antibodies during acute infection.
Blacksell, S., Doust, J., Newton, P., Peacock, S., Day, N., & Dondorp, A. (2006). Transactions of the Royal Society of Tropical Medicine and Hygiene, 100(8), 775-784.
An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).
Mayxay, M., Thongpraseuth, V., Khanthavong, M., Lindeg?rdh, N., Barends, M., Keola, S., Pongvongsa, T., Phompida, S., Phetsouvanh, R., Stepniewska, K., White, N., & Newton, P. (2006). Tropical Medicine & International Health : TM & IH, 11(8), 1157-1165.
Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry
Fernández, F., Cody, R., Green, M., Hampton, C., McGready, R., Sengaloundeth, S., White, N., & Newton, P. (2006). ChemMedChem, 1(7), 702-705.
Manslaughter by fake artesunate in Asia - will Africa be next?
Newton, P., McGready, R., Fernandez, F., Green, Sunjio, M., Bruneton, C., Phanouvong, S., Millet, P., Whitty, C., Talisuna, A., Proux, S., Christophel, E., Malenga, G., Singhasivanon, P., Bojang, K., Kaur, H., Palmer, K., Day, N., Greenwood, B., … White, N. (2006). PLoS Medicine, 3(6), e197.
The comparative accuracy of 8 commercial rapid immunochromatographic assays for the diagnosis of acute dengue virus infection.
Blacksell, S., Newton, P., Bell, D., Kelley, J., Mammen, M., Vaughn, D., Wuthiekanun, V., Sungkakum, A., Nisalak, A., & Day, N. (2006). Clin Infect Dis, 42(8), 1127-1134.
Rickettsial infections and fever, Vientiane, Laos.
Phongmany, S., Rolain, J.-M., Phetsouvanh, R., Blacksell, S., Soukkhaseum, V., Rasachack, B., Phiasakha, K., Soukkhaseum, S., Frichithavong, K., Chu, V., Keolouangkhot, V., Martinez-Aussel, B., Chang, K., Darasavath, C., Rattanavong, O., Sisouphone, S., Mayxay, M., Vidamaly, S., Parola, P., … Newton, P. (2006). Emerging Infectious Diseases, 12(2), 256-262.
Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations.
Newton, P., Ward, S., Angus, B., Chierakul, W., Dondorp, A., Ruangveerayuth, R., Silamut, K., Teerapong, P., Suputtamongkol, Y., Looareesuwan, S., & White, N. (2006). Transactions of the Royal Society of Tropical Medicine and Hygiene, 100(2), 184-186.
Erratum: Manslaughter by fake artesunate in Asia - Will Africa be next? (PLoS Medicine 3,6 DOI: 10.1371/journal.pmed.0030197)
Newton, P., McGready, R., Fernandez, F., Green, Sunjio, M., Bruneton, C., Phanouvong, S., Millet, P., Whitty, C., Talisuna, A., Proux, S., Christophel, E., Malenga, G., Singhasivanon, P., Bojang, K., Kaur, H., Palmer, K., Day, N., Greenwood, B., … White, N. (2006). PLoS Medicine, 3(8), article:1439 - 1439.
Misattribution of central nervous system dysfunction to artesunate.
Newton, P., Day, N., & White, N. (2005). Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 41(11), 1687-1688.
Misattribution of central nervous system dysfunction to artesunate [4] (multiple letters)
Newton, P., Day, N., White, N., Franco-Parades, C., Dismukes, R., Nicolls, D., & Kozarsky, P. (2005). Clinical Infectious Diseases, 41(11), 1687-1689.
Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites.
Anderson, T., Nair, S., Sudimack, D., Williams, J., Mayxay, M., Newton, P., Guthmann, J.-P., Smithuis, F., Tran, T., van den Broek, I., White, N., & Nosten, F. (2005). Mol Biol Evol, 22(12), 2362-2374.
Correction: Estimation of the Total Parasite Biomass in Acute Falciparum Malaria from Plasma PfHRP2
Dondorp, A., Desakorn, V., Pongtavornpinyo, W., Sahassananda, D., Silamut, K., Chotivanich, K., Newton, P., Pitisuttithum, P., Smithyman, A., White, N., & Day, N. (2005). PLOS MEDICINE, 2(10), e390.
Two randomized controlled trials of ceftazidime alone versus ceftazidime in combination with trimethoprim-sulfamethoxazole for the treatment of severe melioidosis.
Chierakul, W., Anunnatsiri, S., Short, J., Maharjan, B., Mootsikapun, P., Simpson, A., Limmathurotsakul, D., Cheng, A., Stepniewska, K., Newton, P., Chaowagul, W., White, N., Peacock, S., Day, N., & Chetchotisakd, P. (2005). Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 41(8), 1105-1113.
Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidos
Chaowagul W, Chierakul W, Simpson AJ, Short, J., Stepniewska, K., Maharjan, B., Rajchanuvong, A., Busarawong, D., Limmathuroksakul, D., Cheng, A., Wuthiekanun, V., Newton, P., White, N., Day, N., & Peacock, S. (2005). Antimicrobial Agents and Chemotherapy., 49(10), 4020-4025.
Sporotrichosis, Plain of Jars, Lao People's Democratic Republic.
Newton, P., Chung, W.-H., Phetsouvanh, R., & White, N. (2005). Emerging Infectious Diseases, 11(9), 1496-1497.
A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos.
Phongmany, S., Phetsouvanh, R., Sisouphone, S., Darasavath, C., Vongphachane, P., Rattanavong, O., Mayxay, M., Ramsay, A., Blacksell, S., Thammavong, C., Syhavong, B., White, N., & Newton, P. (2005). Transactions of the Royal Society of Tropical Medicine and Hygiene, 99(6), 451-458.
Selection strength and hitchhiking around two anti-malarial resistance genes.
Nash, D., Nair, S., Mayxay, M., Newton, P., Guthmann, J.-P., Nosten, F., & Anderson, T. (2005). Proceedings of the Royal Society B: Biological Sciences, 272(1568), 1153-1161.
The global threat of counterfeit drugs: why industry and governments must communicate the dangers.
Cockburn, R., Newton, P., Agyarko, E., Akunyili, D., & White, N. (2005). PLoS Medicine, 2(4), e100.