Data sets contributed were transformed, standardised and pooled according to the WWARN Pharmacology and Clinical Data Management and Statistical Analysis Plans. A population pharmacokinetic-pharmacodynamic model was developed for lumefantrine to understand how body weight, pregnancy, and baseline parasite density influence drug levels.
WWARN is committed to supporting efficient and quality data collection and analysis for antimalarial drug research. As such you can download the code 1 & code 2 files used for this Study Group:
NONMEM is a computer program, NONlinear Mixed Effects Modeling, used by WWARN’s Pharmacometric Scientific Group.