Category
Prof Ric Price was appointed Head of the Clinical Group in WWARN in 2007. He is an infectious disease physician currently on the staff at the Royal Darwin Hospital, Australia, and an honorary consultant at the John Radcliffe Hospital, Oxford. Ric was appointed Professor of Tropical Medicine at the University of Oxford in 2011 and and Professor of Global Health at the Menzies School of Health Research in Darwin, Australia in 2010. The focus of his academic work is the investigation of multidrug resistant malaria and devising strategies for its containment. He coordinates a field site in Papua, Indonesia investigating the diagnosis and management of drug resistant P. falciparum and P. vivax. This work spans clinical studies, epidemiology, pathophysiology, in vitro studies and molecular biology. Ric also chairs the Vivax Working Group of the Asia Pacific Malaria Elimination Network (APMEN).
All Publications
The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: a systematic review and individual patient data meta-analysis
Commons, R., Simpson, J., Thriemer, K., Abreha, T., Adam, I., Anstey, N., Assefa, A., Awab, G., Baird, J., Barber, B., Chu, C., Dahal, P., Daher, A., Davis, T., Dondorp, A., Grigg, M., Humphreys, G., Hwang, J., Karunajeewa, H., … Price, R. (2019). PLOS Medicine, 16(10).
The wwarn clinical trials publication library: a systematically constructed database of plasmodium clinical efficacy trials
Takata, J., Sondo, P., Burrow, R., Maguire, B., Hossain, S., Das, D., Commons, R., Price, R., & Guerin, P. (2019). Transactions of The Royal Society of Tropical Medicine and Hygiene, 113(September 2019), S168 - S169.
Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: A WorldWide Antimalarial Resistance Network individual participant data meta-analysis
Price, R. (2019). Malaria Journal, 18.
Evaluating antimalarial efficacy in single-armed and comparative drug trials using competing risk survival analysis: a simulation study
Dahal, P., Guerin, P., Price, R., Simpson, J., & Stepniewska, K. (2019). BMC Medical Research Methodology, 19.
Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine (vol 91, pg 833, 2014)
Venkatesan, M., Gadalla, N., Stepniewska, K., Dahal, P., Nsanzabana, C., Moriera, C., Price, R., Martensson, A., Rosenthal, P., Dorsey, G., Sutherland, C., Guerin, P., Davis, T., Menard, D., Adam, I., Ademowo, G., Arze, C., Baliraine, F., Berens-Riha, N., … Ogutu, B. (2019). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 3.
Risk of Plasmodium vivax parasitaemia after Plasmodium falciparum infection: a systematic review and meta-analysis
Commons, R., Simpson, J., Thriemer, K., Douglas, N., Humphreys, G., Sibley, C., Guerin, P., & Price, R. (2018). Lancet Infectious Diseases, 19(1), 91-101.
Dealing with indeterminate outcomes in antimalarial efficacy trials: A comparison between complete case analysis, multiple imputation and inverse probability weighting
Dahal, P., Stepniewska, K., Guerin, P., D’Alessandro, U., Price, R., & Simpson, J. (2018). American Journal of Tropical Medicine and Hygiene, 99(S4), 546.
Simulation studies to quantify the impact of competing risk events in a hypothetical scenario of falling antimalarial drug efficacy in single-armed and comparative drug trials
Dahal, P., Guerin, P., Price, R., Simpson, J., & Stepniewska, K. (2018). American Journal of Tropical Medicine and Hygiene, 99(4), 442-443.
The risk of plasmodium vivax parasitaemia after plasmodium falciparum infection: A systematic review and meta-analysis
Commons, R., Simpson, J., Hossain, M., Thriemer, K., Douglas, N., Humphreys, G., Sibley, C., Guerin, P., & Price, R. (2018, October 1). American Journal of Tropical Medicine and Hygiene.
Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis
Kloprogge, F., Newton, P., Mayxay, M., Nosten, F., Ashley, E., McGready, R., van Vugt, V., Proux, S., Price, R., Stepniewska, K., White, N., Guerin, P., & Tarning, J. (2018). PLoS Medicine.
The WWARN Vivax Surveyor: Open access online mapping database for clinical trials of Plasmodium vivax
Commons, R., Thriemer, K., Humphreys, G., Suay, I., Sibley, C., Guerin, P., & Price, R. (2018). American Journal of Tropical Medicine and Hygiene, 97(5S), 86-86.
Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges
Dahal, P., Simpson, J., Dorsey, G., Guérin, P., Price, R., & Stepniewska, K. (2017). Malaria Journal, 16(1), 430.
The Vivax Surveyor: Online mapping database for Plasmodium vivax clinical trials.
Commons, R., Thriemer, K., Humphreys, G., Suay, I., Sibley, C., Guerin, P., & Price, R. (2017). International Journal of Parasitology: Drugs and Drug Resistance, 7(2), 181-190.
Population pharmacokinetic properties of Piperaquine in Falciparum Malaria: an individual participant data-level meta-analysis
Hoglund, R., Workman, L., Edstein, M., Thanh, N., Quang, N., Zongo, I., Ouedraogo, J., Borrmann, S., Mwai, L., Nsanzabana, C., Price, R., Dahal, P., Nosten, F., Ashley, E., Phyo, A., Lwin, K., McGready, R., Day, N., Guerin, P., … Tarning, J. (2017). PLoS Medicine.
Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia
Grist, E., Flegg, J., Humphreys, G., Mas, I., Ashley, E., Humphreys, G., Dhorda, M., Dondorp, A., Hien, T., Maude, R., Mayxay, M., Nosten, F., Newton, P., Price, R., Smithuis, F., White, N., Woodrow, C., Guerin, P., & Gething, P. (2016). International Journal of Health Geographics, 15(37), 1-10.
Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: A systematic review and meta-analysis of individual patient data
Abdulla, S., Achan, J., Yeka, A., D’Alessandro, U., Adam, I., Alemayehu, B., Allan, R., Temu, E., Allen, E., Barnes, K., Anvikar, A., Valecha, N., Arinaitwe, E., Ashley, E., Carrara, V., McGready, R., Nosten, F., Lee, S., White, N., … Kapulu, M. (2016). BMC Medicine, 14(1).
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Ashley, E., Aweeka, F., Barnes, K., Bassat, Q., Borrmann, S., Dahal, P., Davis, T., Deloron, P., Denis, M., Djimde, A., Faucher, J., Genton, B., Guérin, P., Hamed, K., Hodel, E., Huang, L., Jullien, V., Karunajeewa, H., Kiechel, … Workman, L. (2015). BMC Medicine, 13(1).
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis
Abdulla, S., Ashley, E., Bassat, Q., Bethell, D., Bjorkman, A., Borrmann, S., D’Alessandro, U., Dahal, P., Day, N., Diakite, M., Djimde, A., Dondorp, A., Duong, S., Edstein, Fairhurst, R., Faiz, M., Falade, C., Flegg, J., Fogg, C., … Winstanley, P. (2015). Malaria Journal, 14(1).
Genomic epidemiology of the current wave of artemisinin resistant malaria
Amato, R., Miotto, O., Woodrow, C., Almagro-Garcia, J., Sinha, I., Campino, S., Mead, D., Drury, E., Kekre, M., Sanders, M., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Anderson, T., Andrianaranjaka, V., Apinjoh, T., Ashley, E., Auburn, S., Awandare, G., … MalariaGEN Plasmodium falciparum Community Project. (2015).
Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria.
White, N., Ashley, E., Recht, J., Delves, M., Ruecker, A., Smithuis, F., Eziefula, A., Bousema, T., Drakeley, C., Chotivanich, K., Imwong, M., Pukrittayakamee, S., Prachumsri, J., Chu, C., Andolina, C., Bancone, G., Hien, T., Mayxay, M., Taylor, W., … Nosten, F. (2014). Malaria Journal, 13(1), 483.
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.
Venkatesan, M., Gadalla, N., Stepniewska, K., Dahal, P., Nsanzabana, C., Moriera, C., Price, R., Mårtensson, A., Rosenthal, P., Dorsey, G., Sutherland, C., Guérin, P., Davis, T., Ménard, D., Adam, I., Ademowo, G., Arze, C., Baliraine, F., Berens-Riha, N., … Ogutu, B. (2014). American Journal of Tropical Medicine and Hygiene, 91(4), 833-843.
Early parasitological response following artemisinin-containing regimens: a critical review of the literature.
Das, D., Price, R., Bethell, D., Guerin, P., & Stepniewska, K. (2013). Malar J, 12(1).
The power of pooled analysis to inform optimal dosing strategies for Artemisinin Combination Therapies (ACTs)
Guerin, P., Moreira, C., Dahal, P., Piola, P., Stepniewska, K., & Price, R. (2012). Malaria Journal, 11(Suppl 1), P40 - P40.
A systematic review of published antimalarial clinical trials: parasite clearance of artemisinin-containing regimens in the treatment of uncomplicated malaria
Das, D., Bethell, D., Cooksey, R., Anderson, F., Sapchookul, P., Piola, P., Guerin, P., Price, R., & Stepniewska, K. (2012). Malaria Journal, 11(Suppl 1), P37 - P37.
In vivo parasitological measures of artemisinin susceptibility.
Stepniewska, K., Ashley, E., Lee, S., Anstey, N., Barnes, K., Binh, T., D’Alessandro, U., Day, N., de Vries, P., Dorsey, G., Guthmann, J.-P., Mayxay, M., Newton, P., Olliaro, P., Osorio, L., Price, R., Rowland, M., Smithuis, F., Taylor, W., … White, N. (2010). J Infect Dis, 201(4), 570-579.