Professor
Philippe
Guérin
Membre - Comité de pilotage sur le virus Ebola (Ebola SC)
L'Université d’Oxford
Après avoir travaillé comme médecin en France et au Népal, Philippe a rejoint Médecins Sans Frontières où il a acquis une vaste expérience en tant que chercheur travaillant sur le terrain et sur le paludisme et la tuberculose. Il a été pendant six ans directeur scientifique d'Epicentre à Paris, un centre collaborateur de l'Organisation mondiale de la santé pour la recherche en épidémiologie et la réponse aux maladies émergentes. Auparavant, il a été conseiller principal à l'Institut norvégien de santé publique pendant trois ans.
Philippe est directeur de l'Observatoire de données sur les maladies infectieuses (IDDO), dont la mission est de rassembler et d'agréger des données cliniques, laboratoire et épidémiologiques sur certaines maladies sélectionnées liées à la pauvreté et sur les infections émergentes. IDDO s’appuie sur le succès du réseau WWARN (WorldWide Antimalarial Resistance Network), une plateforme scientifiquement indépendante et multidisciplinaire, créée en 2009 pour fournir les informations nécessaires pour empêcher ou alléger la résistance aux médicaments antipaludiques et de cette manière réduire la mortalité, et la morbidité du paludisme.
All Publications
Statistical estimation of malaria genotype frequencies: a Bayesian approach
Taylor, A., Flegg, J., Dorsey, G., Guerin, P., & Holmes, C. (2013). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 18, 67-67.
Shotgun nanoLC-MS/MS proteogenomics to document MALDI-TOF biomarkers for screening new members of the Ruegeria genus.
Christie-Oleza, J., Piña-Villalonga, J., Guerin, P., Miotello, G., Bosch, R., Nogales, B., & Armengaud, J. (2013). Environmental Microbiology, 15(1), 133-147.
Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority trial.
Schramm, B., Valeh, P., Baudin, E., Mazinda, C., Smith, R., Pinoges, L., Dhorda, M., Boum, Y., Sundaygar, T., Zolia, Y., Jones, J., Comte, E., Houzé, P., Jullien, V., Carn, G., Ashley, E., & Guérin, P. (2013). Malar J, 12(1).
Tolerability and safety of artesunate-amodiaquine and artemether-lumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria: two open-label, randomized trials in Nimba County, Liberia.
Schramm, B., Valeh, P., Baudin, E., Mazinda, C., Smith, R., Pinoges, L., Sundaygar, T., Zolia, Y., Jones, J., Comte, E., Bruneel, A., Branger, M., Jullien, V., Carn, G., Kiechel, Ashley, E., & Guérin, P. (2013). Malar J, 12(1).
Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum.
Flegg, J., Patil, A., Venkatesan, M., Roper, C., Naidoo, I., Hay, S., Sibley, C., & Guerin, P. (2013). Malar J, 12(1).
Early parasitological response following artemisinin-containing regimens: a critical review of the literature.
Das, D., Price, R., Bethell, D., Guerin, P., & Stepniewska, K. (2013). Malar J, 12(1).
Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000-2011.
Gharbi, M., Flegg, J., Hubert, V., Kendjo, E., Metcalf, J., Bertaux, L., Guérin, P., Le Bras, J., Aboubaca, A., Agnamey, P., Angoulvant, A., Barbut, P., Basset, D., Belkadi, G., Bellanger, A., Bemba, D., Benoit-Vica, F., Berry, A., Bigel, M., … Garabedian, C. (2013). Malar J, 12(1).
Made in Europe: will artemisinin resistance emerge in French Guiana?
Nacher, M., Guérin, P., Demar-Pierre, M., Djossou, F., Nosten, F., & Carme, B. (2013). Malar J, 12(1).
Impact of malaria during pregnancy on pregnancy outcomes in a Ugandan prospective cohort with intensive malaria screening and prompt treatment.
De Beaudrap, P., Turyakira, E., White, L., Nabasumba, C., Tumwebaze, B., Muehlenbachs, A., Guérin, P., Boum, Y., McGready, R., & Piola, P. (2013). Malaria Journal, 1.
Mitigating the threat of artemisinin resistance in Africa: improvement of drug-resistance surveillance and response systems.
Talisuna, A., Karema, C., Ogutu, B., Juma, E., Logedi, J., Nyandigisi, A., Mulenga, M., Mbacham, W., Roper, C., Guerin, P., D’Alessandro, U., & Snow, R. (2012). Lancet Infect Dis, 12(11), 888-896.
Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda.
Tarning, J., Kloprogge, F., Piola, P., Dhorda, M., Muwanga, S., Turyakira, E., Nuengchamnong, N., Nosten, F., Day, N., White, N., Guerin, P., & Lindegardh, N. (2012). Malar J, 11(1).
Optimal sampling designs for accurate estimation of parasite clearance in the context of artemisinin resistance
Flegg, J., Guerin, P., Nosten, F., Dondorp, A., Fairhurst, R., Socheat, D., Borrmann, S., Björkman, A., Mårtensson, A., Mayxay, M., Newton, P., Bethell, D., Se, Y., Noedl, H., Djimde, A., White, N., & Stepniewska, K. (2012). Malaria Journal, 11(Suppl 1), P39 - P39.
Longitudinal study assessing the return of chloroquine susceptibility of Plasmodiun falciparum isolates from travelers returning from West Africa
Gharbi, M., Flegg, J., Hubert, V., Kendjo, E., Metcalf, J., Guerin, P., & Le Bras, J. (2012). Malaria Journal, 11(Suppl 1), P38 - P38.
Childhood imported malaria: could we have suppressed risk factors in some children?
Pillai, S., Siriez, J.-Y., Kendjo, E., Houze, S., Guerin, P., & Le Bras, J. (2012). Malaria Journal, 11(Suppl 1), P53 - P53.
The power of pooled analysis to inform optimal dosing strategies for Artemisinin Combination Therapies (ACTs)
Guerin, P., Moreira, C., Dahal, P., Piola, P., Stepniewska, K., & Price, R. (2012). Malaria Journal, 11(Suppl 1), P40 - P40.
A systematic review of published antimalarial clinical trials: parasite clearance of artemisinin-containing regimens in the treatment of uncomplicated malaria
Das, D., Bethell, D., Cooksey, R., Anderson, F., Sapchookul, P., Piola, P., Guerin, P., Price, R., & Stepniewska, K. (2012). Malaria Journal, 11(Suppl 1), P37 - P37.
The power of pooled analysis: WWARN community reaches a critical mass of data
Guerin, P., & Sibley, C. (2012). Malaria Journal, 11(Suppl 1), O38 - O38.
A Bayesian model for estimating with-in host P. falciparum haplotype frequencies
Taylor, A., Flegg, J., Guerin, P., Roper, C., & Holmes, C. (2012). Malaria Journal, 11(Suppl 1), P36 - P36.
Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial.
Espié, E., Lima, A., Atua, B., Dhorda, M., Flévaud, L., Sompwe, E., Palma Urrutia, P., & Guerin, P. (2012). Malaria Journal, 11(1).
Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial.
Muehlenbachs, A., Nabasumba, C., McGready, R., Turyakira, E., Tumwebaze, B., Dhorda, M., Nyehangane, D., Nalusaji, A., Nosten, F., Guerin, P., & Piola, P. (2012). Malaria Journal, 1.
Mapping the aetiology of non-malarial febrile illness in Southeast Asia through a systematic review--terra incognita impairing treatment policies.
Acestor, N., Cooksey, R., Newton, P., Menard, D., Guerin, P., Nakagawa, J., Christophel, E., Gonzalez, I., & Bell, D. (2012). PloS One, 7(9).
Evaluation of a rapid test for the diagnosis of cholera in the absence of a gold standard.
Page, A., Alberti, K., Mondonge, V., Rauzier, J., Quilici, M., & Guerin, P. (2012). PloS One, 7(5).
Performance of a histidine-rich protein 2 rapid diagnostic test, Paracheck Pf®, for detection of malaria infections in Ugandan pregnant women
Dhorda, M., Piola, P., Nyehangane, D., Tumwebaze, B., Nalusaji, A., Nabasumba, C., Turyakira, E., McGready, R., Ashley, E., Guerin, P., & Snounou, G. (2012). American Journal of Tropical Medicine and Hygiene, 86(1), 93-95.
The primacy of public health considerations in defining poor quality medicines.
Newton, P., Amin, A., Bird, C., Passmore, P., Dukes, G., Tomson, G., Simons, B., Bate, R., Guerin, P., & White, N. (2011). PLoS Medicine, 8(12).
The threat of artemisinin-resistant malaria.
Dondorp, A., Fairhurst, R., Slutsker, L., Macarthur, J., Breman, J., Guerin, P., Wellems, T., Ringwald, P., Newman, R., & Plowe, C. (2011). N Engl J Med, 365(12), 1073-1075.