Professor
Philippe
Guérin
Membre - Comité de pilotage sur le virus Ebola (Ebola SC)
L'Université d’Oxford
Après avoir travaillé comme médecin en France et au Népal, Philippe a rejoint Médecins Sans Frontières où il a acquis une vaste expérience en tant que chercheur travaillant sur le terrain et sur le paludisme et la tuberculose. Il a été pendant six ans directeur scientifique d'Epicentre à Paris, un centre collaborateur de l'Organisation mondiale de la santé pour la recherche en épidémiologie et la réponse aux maladies émergentes. Auparavant, il a été conseiller principal à l'Institut norvégien de santé publique pendant trois ans.
Philippe est directeur de l'Observatoire de données sur les maladies infectieuses (IDDO), dont la mission est de rassembler et d'agréger des données cliniques, laboratoire et épidémiologiques sur certaines maladies sélectionnées liées à la pauvreté et sur les infections émergentes. IDDO s’appuie sur le succès du réseau WWARN (WorldWide Antimalarial Resistance Network), une plateforme scientifiquement indépendante et multidisciplinaire, créée en 2009 pour fournir les informations nécessaires pour empêcher ou alléger la résistance aux médicaments antipaludiques et de cette manière réduire la mortalité, et la morbidité du paludisme.
All Publications
Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: A WorldWide Antimalarial Resistance Network individual participant data meta-analysis
Price, R. (2019). Malaria Journal, 18.
The effect of dose on the antimalarial efficacy of artesunate-mefloquine against Plasmodium falciparum malaria: a protocol for systematic review and individual patient data (IPD) meta-analysis
Mansoor, R., Dahal, P., Humphreys, G., Guerin, P., Ashley, E., & Stepniewska, K. (2019). BMJ Open, 9(6).
Optimal duration of follow-up for assessing antimalarial efficacy in pregnancy: a retrospective analysis of a cohort followed up until delivery on the Thailand-Myanmar border
Saito, M., Mansoor, R., Wiladphaingern, J., Paw, M., Pimanpanarak, M., Proux, S., Guérin, P., White, N., Nosten, F., & McGready, R. (2019). Open Forum Infectious Diseases, 6(7).
Evaluating antimalarial efficacy in single-armed and comparative drug trials using competing risk survival analysis: a simulation study
Dahal, P., Guerin, P., Price, R., Simpson, J., & Stepniewska, K. (2019). BMC Medical Research Methodology, 19.
Malaria control in India: a national perspective in a regional and global fight to eliminate malaria
Guerin, P., Dhorda, M., Ganguly, N., & Sibley, C. (2019). Journal of Vector Borne Diseases, 56(1), 41-45.
Microbiology Investigation Criteria for Reporting Objectively (MICRO): a framework for the reporting and interpretation of clinical microbiology data
Turner, P., Fox-Lewis, A., Shrestha, P., Dance, D., Wangrangsimakul, T., Cusack, T.-P., Ling, C., Hopkins, J., Roberts, T., Limmathurotsakul, D., Cooper, B., Dunachie, S., Moore, C., Dolecek, C., Van Doorn, H., Guerin, P., Day, N., & Ashley, E. (2019). BMC Medicine, 17(1), 70.
Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis
Ashley, E., Dhorda, M., Dondorp, A., Fanello, C., Guérin, P., Humphreys, G., Kennon, K., Mayxay, M., Nosten, F., Phyo, A., Sibley, C., Sondo, P., Stepniewska, K., White, N., & Woodrow, C. (2019). BMC Medicine, 1(17).
ESTIMATION OF INCIDENCE RISK OF MORTALITY AND SERIOUS ADVERSE EVENTS FOR ANTILEISHMANIAL THERAPIES: AN INFECTIOUS DISEASES DATA OBSERVATORY SYSTEMATIC REVIEW OF PUBLISHED LITERATURE FROM 1980 TO 2018
Singh, S., Dahal, P., Ngu, R., Maguire, B., Olliaro, P., Stepniewska, K., & Guerin, P. (2019). TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 113, S69 - S69.
SYSTEMATIC REVIEW OF SCRUB TYPHUS STUDY LANDSCAPE: PROTOCOL AND PRELIMINARY LITERATURE SEARCH RESULTS
Saraswati, K., Maguire, B., Singh, S., Day, N., & Guerin, P. (2019). TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 113, S230 - S231.
SYSTEMATIC REVIEW OF SCRUB TYPHUS DRUG EFFICACY STUDY LANDSCAPE
Saraswati, K., Maguire, B., Singh, S., Day, N., & Guerin, P. (2019). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 101, 37-38.
Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine (vol 91, pg 833, 2014)
Venkatesan, M., Gadalla, N., Stepniewska, K., Dahal, P., Nsanzabana, C., Moriera, C., Price, R., Martensson, A., Rosenthal, P., Dorsey, G., Sutherland, C., Guerin, P., Davis, T., Menard, D., Adam, I., Ademowo, G., Arze, C., Baliraine, F., Berens-Riha, N., … Ogutu, B. (2019). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 3.
Risk of Plasmodium vivax parasitaemia after Plasmodium falciparum infection: a systematic review and meta-analysis
Commons, R., Simpson, J., Thriemer, K., Douglas, N., Humphreys, G., Sibley, C., Guerin, P., & Price, R. (2018). Lancet Infectious Diseases, 19(1), 91-101.
The arrhythmogenic cardiotoxicity of the quinoline and structurally related antimalarial drugs: a systematic review
Haeusler, I., Chan, X., Guérin, P., & White, N. (2018). BMC Medicine, 16(200), 1-13.
Complex interactions between malaria and malnutrition: a systematic literature review
Das, D., Grais, R., Okiro, E., Stepniewska, K., Mansoor, R., Van Der Kam, S., Terlouw, D., Tarning, J., Barnes, K., & Guerin, P. (2018). BMC Medicine, 16(1), 186.
A qualitative study of barriers and enablers to the establishment of robust clinical research data management systems in low and middle income countries
Jule, A., Ndiaye, M., Gaye, O., Koukouikila, F., Ntoumi, F., Olliaro, P., Guerin, P., Lang, T., & Marsh, V. (2018). The American Journal of Tropical Medicine and Hygiene, 99(4), 480-480.
Simulation studies to quantify the impact of competing risk events in a hypothetical scenario of falling antimalarial drug efficacy in single-armed and comparative drug trials
Dahal, P., Guerin, P., Price, R., Simpson, J., & Stepniewska, K. (2018). American Journal of Tropical Medicine and Hygiene, 99(4), 442-443.
Dealing with indeterminate outcomes in antimalarial efficacy trials: A comparison between complete case analysis, multiple imputation and inverse probability weighting
Dahal, P., Stepniewska, K., Guerin, P., D’Alessandro, U., Price, R., & Simpson, J. (2018). American Journal of Tropical Medicine and Hygiene, 99(S4), 546.
The risk of plasmodium vivax parasitaemia after plasmodium falciparum infection: A systematic review and meta-analysis
Commons, R., Simpson, J., Hossain, M., Thriemer, K., Douglas, N., Humphreys, G., Sibley, C., Guerin, P., & Price, R. (2018, October 1). American Journal of Tropical Medicine and Hygiene.
Secondary analysis and participation of those at the data source
Merson, L., Guerin, P., Barnes, K., Ntoumi, F., & Gaye, O. (2018). Lancet Global Health, 6(9), E965.
Enumerating the economic cost of antimicrobial resistance per antibiotic consumed to inform the evaluation of interventions affecting their use
Shrestha, P., Cooper, B., Coast, J., Oppong, R., Do, N., Pudha, T., Guerin, P., Wertheim, H., & Lubell, Y. (2018). Antimicrobial Resistance and Infection Control, 98(7).
The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis
Commons, R., Simpson, J., Thriemer, K., Humphreys, G., Abreha, T., Alemu, S., Añez, A., Anstey, N., Awab, G., Baird, J., Barber, B., Borghini-Fuhrer, I., Chu, C., D’Alessandro, U., Dahal, P., Daher, A., De Vries, P., Erhart, A., Gomes, M., … Woodrow, C. (2018). Lancet Infectious Diseases, 18(9), 1025-1034.
Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis
Kloprogge, F., Newton, P., Mayxay, M., Nosten, F., Ashley, E., McGready, R., van Vugt, V., Proux, S., Price, R., Stepniewska, K., White, N., Guerin, P., & Tarning, J. (2018). PLoS Medicine.
Malaria and nutritional status among children with severe acute malnutrition in Niger: A prospective cohort study
Oldenburg, C., Guerin, P., Berthé, F., Grais, R., & Isanaka, S. (2018). Clinical Infectious Diseases, 67(7), 1027-1034.
An inventory of supranational antimicrobial resistance surveillance networks involving low- and middle-income countries since 2000
Ashley, E., Recht, J., Chua, A., Dance, D., Dhorda, M., Thomas, N., Ranganathan, N., Turner, P., Guerin, P., White, N., & Day, N. (2018). Journal of Antimicrobial Chemotherapy.
Molecular markers of resistance to amodiaquine plus sulfadoxine-pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger
Grais, R., Laminou, I., Woi-Messe, L., Makarimi, R., Bouriema, S., Langendorf, C., Amambua-Ngwa, A., D’Alessandro, U., Guérin, P., Fandeur, T., & Sibley, C. (2018). Malaria Journal, 17(1), 98.