Professor
Nicholas
White
Professor of Tropical Medicine
Nick White is a Professor of Tropical Medicine at Mahidol University Thailand and at the University of Oxford, and a consultant physician in acute general medicine at the John Radcliffe Hospital, Oxford, UK. He was Chair of the WWARN Board until 2016, and remains a member of the IDDO Board.
He also co-chaired the World Health Organization antimalarial treatment guidelines committee and the WHO Global Malaria Programme case management cluster. Prof White has served on the editorial advisory boards of international journals including The Lancet and PLoS Medicine. He has contributed to over 1000 peer reviewed scientific publications and has written over 50 book chapters.
Nick White began his work in Thailand in 1980 with the Wellcome Trust Mahidol Oxford Tropical Medicine Research Unit, a collaborative research programme between Mahidol and Oxford Universities. In 1986 he was appointed as Director of the Thailand Unit, and more recently Chair of the Wellcome Trust SE Asian Tropical Medicine Research Programmes.
Nick White’s contribution to tropical medicine and global health was recognised with a UK Knighthood in 2017. His research interests include the epidemiology, pathophysiology and treatment of malaria, melioidosis, typhoid, leptospirosis, dengue, haemorrhagic fever, Japanese encephalitis and tuberculosis.
All Publications
A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.
Mayxay, M., Keomany, S., Khanthavong, M., Souvannasing, P., Stepniewska, K., Khomthilath, T., Keola, S., Pongvongsa, T., Phompida, S., Ubben, D., Valecha, N., White, N., & Newton, P. (2010). Am J Trop Med Hyg, 83(6), 1221-1229.
The infective causes of hepatitis and jaundice amongst hospitalised patients in Vientiane, Laos.
Syhavong, B., Rasachack, B., Smythe, L., Rolain, J.-M., Roque-Afonso, A.-M., Jenjaroen, K., Soukkhaserm, V., Phongmany, S., Phetsouvanh, R., Soukkhaserm, S., Thammavong, T., Mayxay, M., Blacksell, S., Barnes, E., Parola, P., Dussaix, E., Raoult, D., Humphreys, I., Klenerman, P., … Newton, P. (2010). Trans R Soc Trop Med Hyg, 104(7), 475-483.
In vivo parasitological measures of artemisinin susceptibility.
Stepniewska, K., Ashley, E., Lee, S., Anstey, N., Barnes, K., Binh, T., D’Alessandro, U., Day, N., de Vries, P., Dorsey, G., Guthmann, J.-P., Mayxay, M., Newton, P., Olliaro, P., Osorio, L., Price, R., Rowland, M., Smithuis, F., Taylor, W., … White, N. (2010). J Infect Dis, 201(4), 570-579.
Counterfeit and Substandard Anti-infectives in Developing Countries
Newton, P., Fernández, F., Green, M., Primo-Carpenter, J., & White, N. (2010). In Antimicrobial Resistance in Developing Countries (pp. 413-443). Springer Nature.
Implementation of a reference standard and proficiency testing programme by the World Wide Antimalarial Resistance Network (WWARN).
Lourens, C., Watkins, Barnes, K., Sibley, C., Guerin, P., White, N., & Lindegardh, N. (2010). Malaria Journal, 9(1).
Guidelines for field surveys of the quality of medicines: a proposal.
Newton, P., Lee, S., Goodman, C., Fernández, F., Yeung, S., Phanouvong, S., Kaur, H., Amin, A., Whitty, C., Kokwaro, G., Lindegårdh, N., Lukulay, P., White, L., Day, N., & White, N. (2009). PLoS Medicine, 3.
N-acetylcysteine as adjunctive treatment in severe malaria: a randomized, double-blinded placebo-controlled clinical trial.
Charunwatthana, P., Abul Faiz, M., Ruangveerayut, R., Maude, R., Rahman, M., Roberts, L., Moore, K., Bin Yunus, E., Hoque, M., Hasan, M., Lee, S., Pukrittayakamee, S., Newton, P., White, N., Day, N., & Dondorp, A. (2009). Crit Care Med, 37(2), 516-522.
Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis.
Zwang, J., Ashley, E., Karema, C., D’Alessandro, U., Smithuis, F., Dorsey, G., Janssens, B., Mayxay, M., Newton, P., Singhasivanon, P., Stepniewska, K., White, N., & Nosten, F. (2009). PloS One, 4(7).
Characterization of "Yaa Chud" Medicine on the Thailand-Myanmar border: selecting for drug-resistant malaria and threatening public health.
Newton, P., Hampton, C., Alter-Hall, K., Teerwarakulpana, T., Prakongpan, S., Ruangveerayuth, R., White, N., Day, N., Tudino, M., Mancuso, N., & Fernández, F. (2008). Am J Trop Med Hyg, 79(5), 662-669.
Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar.
Imwong, M., Pukrittayakamee, S., Pongtavornpinyo, W., Nakeesathit, S., Nair, S., Newton, P., Nosten, F., Anderson, T., Dondorp, A., Day, N., & White, N. (2008). Antimicrob Agents Chemother, 52(7), 2657-2659.
The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria.
Lee, S., Stepniewska, K., Anstey, N., Ashley, E., Barnes, K., Binh, T., D’Alessandro, U., Day, N., de Vries, P., Dorsey, G., Guthmann, J., Mayxay, M., Newton, P., Nosten, F., Olliaro, P., Osario, L., Pinoges, L., Price, R., Rowland, M., … White, N. (2008). Malaria Journal, 7(1).
Letters to the editors
Newton, P., Mayxay, M., Taylor, A., & White, N. (2007). Tropical Medicine and International Health, 12(10), 1272-1273.
World Antimalarial Resistance Network I: clinical efficacy of antimalarial drugs.
Price, R., Dorsey, G., Ashley, E., Barnes, K., Baird, J., d’Alessandro, U., Guerin, P., Laufer, M., Naidoo, I., Nosten, F., Olliaro, P., Plowe, C., Ringwald, P., Sibley, C., Stepniewska, K., & White, N. (2007). Malaria Journal, 6, 119.
Contrasting genetic structure in Plasmodium vivax populations from Asia and South America.
Imwong, M., Nair, S., Pukrittayakamee, S., Sudimack, D., Williams, J., Mayxay, M., Newton, P., Kim, J., Nandy, A., Osorio, L., Carlton, J., White, N., Day, N., & Anderson, T. (2007). Int J Parasitol, 37(8-9), 1013-1022.
Combined molecular and clinical assessment of Plasmodium falciparum antimalarial drug resistance in the Lao People's Democratic Republic (Laos).
Mayxay, M., Nair, S., Sudimack, D., Imwong, M., Tanomsing, N., Pongvongsa, T., Phompida, S., Phetsouvanh, R., White, N., Anderson, T., & Newton, P. (2007). The American Journal of Tropical Medicine and Hygiene, 77(1), 36-43.
Diagnosis and management of malaria by rural community health providers in the Lao People's Democratic Republic (Laos).
Mayxay, M., Pongvongsa, T., Phompida, S., Phetsouvanh, R., White, N., & Newton, P. (2007). Tropical Medicine & International Health : TM & IH, 12(4), 540-546.
Thiamin deficiency and uncomplicated falciparum malaria in Laos.
Mayxay, M., Taylor, A., Khanthavong, M., Keola, S., Pongvongsa, T., Phompida, S., Phetsouvanh, R., White, N., & Newton, P. (2007). Tropical Medicine & International Health : TM & IH, 12(3), 363-369.
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
Mayxay, M., Barends, M., Brockman, A., Jaidee, A., Nair, S., Sudimack, D., Pongvongsa, T., Phompida, S., Phetsouvanh, R., Anderson, T., White, N., & Newton, P. (2007). The American Journal of Tropical Medicine and Hygiene, 76(2), 245-250.
Fast detection and identification of counterfeit antimalarial tablets by Raman spectroscopy
de Veij, M., Vandenabeele, P., Hall, K., Fernandez, F., Green, M., White, N., Dondorp, A., Newton, P., & Moens, L. (2007). Journal of Raman Spectroscopy, 38(2), 181-187.
Untitled
Newton, P., Mayxay, M., Taylor, A., & White, N. (2007). TROPICAL MEDICINE & INTERNATIONAL HEALTH, 12(10), 1272-1273.
The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.
Newton, P., Barnes, K., Smith, P., Evans, A., Chierakul, W., Ruangveerayuth, R., & White, N. (2006). Eur J Clin Pharmacol, 62(12), 1003-1009.
Causes of community-acquired bacteremia and patterns of antimicrobial resistance in Vientiane, Laos.
Phetsouvanh, R., Phongmany, S., Soukaloun, D., Rasachak, B., Soukhaseum, V., Soukhaseum, S., Frichithavong, K., Khounnorath, S., Pengdee, B., Phiasakha, K., Chu, V., Luangxay, K., Rattanavong, S., Sisouk, K., Keolouangkot, V., Mayxay, M., Ramsay, A., Blacksell, S., Campbell, J., … Newton, P. (2006). Am J Trop Med Hyg, 75(5), 978-985.
Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin M antibodies in Laos.
Blacksell, S., Smythe, L., Phetsouvanh, R., Dohnt, M., Hartskeerl, R., Symonds, M., Slack, A., Vongsouvath, M., Davong, V., Lattana, O., Phongmany, S., Keolouangkot, V., White, N., Day, N., & Newton, P. (2006). Clin Vaccine Immunol, 13(10), 1166-1169.
Counterfeit anti-infective drugs.
Newton, P., Green, M., Fernández, F., Day, N., & White, N. (2006). Lancet Infect Dis, 6(9), 602-613.
An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).
Mayxay, M., Thongpraseuth, V., Khanthavong, M., Lindeg?rdh, N., Barends, M., Keola, S., Pongvongsa, T., Phompida, S., Phetsouvanh, R., Stepniewska, K., White, N., & Newton, P. (2006). Tropical Medicine & International Health : TM & IH, 11(8), 1157-1165.