Professor
Nicholas
White
Professor of Tropical Medicine
Nick White is a Professor of Tropical Medicine at Mahidol University Thailand and at the University of Oxford, and a consultant physician in acute general medicine at the John Radcliffe Hospital, Oxford, UK. He was Chair of the WWARN Board until 2016, and remains a member of the IDDO Board.
He also co-chaired the World Health Organization antimalarial treatment guidelines committee and the WHO Global Malaria Programme case management cluster. Prof White has served on the editorial advisory boards of international journals including The Lancet and PLoS Medicine. He has contributed to over 1000 peer reviewed scientific publications and has written over 50 book chapters.
Nick White began his work in Thailand in 1980 with the Wellcome Trust Mahidol Oxford Tropical Medicine Research Unit, a collaborative research programme between Mahidol and Oxford Universities. In 1986 he was appointed as Director of the Thailand Unit, and more recently Chair of the Wellcome Trust SE Asian Tropical Medicine Research Programmes.
Nick White’s contribution to tropical medicine and global health was recognised with a UK Knighthood in 2017. His research interests include the epidemiology, pathophysiology and treatment of malaria, melioidosis, typhoid, leptospirosis, dengue, haemorrhagic fever, Japanese encephalitis and tuberculosis.
All Publications
Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria
Watson, J., Taylor, W., Bancone, G., Chu, C., Jittamala, P., & White, N. (2018). PLoS Neglected Tropical Diseases, 12(4), e0006440.
Characterising blood stage antimalarial drug minimum inhibitory concentrations in vivo using reinfection patterns
Watson, J., Chu, C., Tarning, J., & White, N. (2018). Antimicrobial Agents and Chemotherapy, 62(7), e02476 - 17.
An inventory of supranational antimicrobial resistance surveillance networks involving low- and middle-income countries since 2000
Ashley, E., Recht, J., Chua, A., Dance, D., Dhorda, M., Thomas, N., Ranganathan, N., Turner, P., Guerin, P., White, N., & Day, N. (2018). Journal of Antimicrobial Chemotherapy.
Why do people participate in mass anti-malarial administration? Findings from a qualitative study in Nong District, Savannakhet Province, Lao PDR (Laos)
Adhikari, B., Phommasone, K., Kommarasy, P., Soundala, X., Souvanthong, P., Pongvongsa, T., Henriques, G., Newton, P., White, N., Day, N., Dondorp, A., von Seidlein, L., Mayxay, M., Cheah, P., & Pell, C. (2018). Malaria Journal, 17(1).
A MIXED METHOD STUDY OF HEALTH SEEKING BEHAVIOR FOR FEBRILE ILLNESSES AND ITS IMPLICATIONS FOR MALARIA CONTROL AND ELIMINATION IN SAVANNAKHET PROVINCE, LAO PDR
Adhikari, B., Phommasone, K., Pongvosa, T., Koummarasy, P., Soundala, X., Henriques, G., Sirithiranont, P., Parker, D., von Seidlein, L., White, N., Day, N., Dondorp, A., Newton, P., Cheah, P., Pell, C., & Mayxay, M. (2018). In AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (Vols. 99, Issues 4, pp. 125-125).
Split dosing of artemisinins does not improve antimalarial therapeutic efficacy
White, N., Watson, J., & Ashley, E. (2017). Scientific Reports, 7(12132), 1-5.
Modelling primaquine-induced haemolysis in G6PD deficiency
White, N., Watson, J., Taylor, R., Menard, D., & Kheng, S. (2017). ELife.
Population pharmacokinetic properties of Piperaquine in Falciparum Malaria: an individual participant data-level meta-analysis
Hoglund, R., Workman, L., Edstein, M., Thanh, N., Quang, N., Zongo, I., Ouedraogo, J., Borrmann, S., Mwai, L., Nsanzabana, C., Price, R., Dahal, P., Nosten, F., Ashley, E., Phyo, A., Lwin, K., McGready, R., Day, N., Guerin, P., … Tarning, J. (2017). PLoS Medicine.
Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia
Grist, E., Flegg, J., Humphreys, G., Mas, I., Ashley, E., Humphreys, G., Dhorda, M., Dondorp, A., Hien, T., Maude, R., Mayxay, M., Nosten, F., Newton, P., Price, R., Smithuis, F., White, N., Woodrow, C., Guerin, P., & Gething, P. (2016). International Journal of Health Geographics, 15(37), 1-10.
Geographic distribution of amino acid mutations in DHFR and DHPS in Plasmodium vivax isolates from Lao PDR, India and Colombia
Saralamba, N., Nakeesathit, S., Mayxay, M., Newton, P., Osorio, L., Kim, J.-R., White, N., Day, N., Dondorp, A., & Imwong, M. (2016). Malaria Journal, 15(1).
Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)
Phommasone, K., Adhikari, B., Henriques, G., Pongvongsa, T., Phongmany, P., Von Seidlein, L., White, N., Day, N., Dondorp, A., Newton, P., Imwong, M., & Mayxay, M. (2016). Malaria Journal, 15(1).
Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: A systematic review and meta-analysis of individual patient data
Abdulla, S., Achan, J., Yeka, A., D’Alessandro, U., Adam, I., Alemayehu, B., Allan, R., Temu, E., Allen, E., Barnes, K., Anvikar, A., Valecha, N., Arinaitwe, E., Ashley, E., Carrara, V., McGready, R., Nosten, F., Lee, S., White, N., … Kapulu, M. (2016). BMC Medicine, 14(1).
Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria
Wattanakul, T., Teerapong, P, P., Plewes, K., Newton, P., Chierakul, W., Silamut, K., Chotivanich, K., Ruangweerayut, R., White, N., Dondorp, A., & Tarning, J. (2016). Malaria Journal, 15.
Performance of C-reactive protein and procalcitonin to distinguish viral from bacterial and malarial causes of fever in Southeast Asia
Lubell, Y., Blacksell, S., Dunachie, S., Tanganuchitcharnchai, A., Althaus, T., Watthanaworawit, W., Paris, D., Mayxay, M., Peto, T., Dondorp, A., White, N., Day, N., Nosten, F., Newton, P., & Turner, P. (2015). BMC Infectious Diseases, 15(1).
Artemisinin resistance in Myanmar – Authors' reply
Imwong, M., Tun, K., Hlaing, T., Grist, E., Guerin, P., Smithuis, F., Dondorp, A., Day, N., Nosten, F., White, N., & Woodrow, C. (2015). The Lancet Infectious Diseases, 15(9), 1002-1003.
Past and new challenges for malaria control and elimination: the role of operational research for innovation in designing interventions.
Guyant, P., Corbel, V., Guérin, P., Lautissier, A., Nosten, F., Boyer, S., Coosemans, M., Dondorp, A., Sinou, V., Yeung, S., & White, N. (2015). Malaria Journal, 14, 279.
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Tun, K., Imwong, M., Lwin, K., Win, A., Hlaing, T., Hlaing, T., Lin, K., Kyaw, M., Plewes, K., Faiz, M., Dhorda, M., Cheah, P., Pukrittayakamee, S., Ashley, E., Anderson, T., Nair, S., McDew-White, M., Flegg, J., Grist, E., … Woodrow, C. (2015). The Lancet Infectious Diseases, 15(4), 415-421.
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.
Takala-Harrison, S., Jacob, C., Arze, C., Cummings, M., Silva, J., Dondorp, A., Fukuda, M., Hien, T., Mayxay, M., Noedl, H., Nosten, F., Kyaw, M., Nhien, N., Imwong, M., Bethell, D., Se, Y., Lon, C., Tyner, S., Saunders, D., … Plowe, C. (2015). The Journal of Infectious Diseases, 211(5), 670-679.
Quality assurance of drugs used in clinical trials: proposal for adapting guidelines
Newton, P., Schellenberg, D., Ashley, E., Ravinetto, R., Green, M., ter Kuile, F., Tabernero, P., White, N., & Guerin, P. (2015). BMJ, 350.
Genetic architecture of artemisinin-resistant Plasmodium falciparum
Miotto, O., Amato, R., Ashley, E., MacInnis, B., Almagro-Garcia, J., Amaratunga, C., Lim, P., Mead, D., Oyola, S., Dhorda, M., Imwong, M., Woodrow, C., Manske, M., Stalker, J., Drury, E., Campino, S., Amenga-Etego, L., Thanh, T.-N., Tran, H., … Kwiatkowski, D. (2015). Nature Genetics, 47(3), 226-234.
HUMORAL IMMUNITY CONTRIBUTES TO CLEARANCE OF ARTEMISININ-RESISTANT PARASITES IN SOUTHEAST ASIA
Travassos, M., Bailey, J., Takala-Harrison, S., Manwani, B., Berry, A., Pablo, J., Jasinskas, A., Nakajima, R., Adams, M., Ashley, E., Dhorda, M., Nosten, F., Phyo, A., Newton, P., Mayxay, M., Dondorp, A., Tran, T., Han, K.-T., Kway, M., … Plowe, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 289-289.
LARGE-SCALE SCANS FOR GENOMIC REGIONS UNDER POSITIVE SELECTION IN SOUTHEAST ASIAN PLASMODIUM FALCIPARUM REVEAL GENES OF PUBLIC HEALTH IMPORTANCE
Jacob, C., Arze, C., Saunders, D., Lanteri, C., Fairhurst, R., Amaratunga, C., Tan, J., Miller, B., Miotto, O., MacInnis, B., Lim, P., Suon, S., Yi, P., Sreng, S., Jittamala, P., Chotivanich, K., Imwong, M., Chutasmit, K., Suchatsoonthorn, C., … Plowe, C. (2015). AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 93(4), 560-560.
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: A systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Ashley, E., Aweeka, F., Barnes, K., Bassat, Q., Borrmann, S., Dahal, P., Davis, T., Deloron, P., Denis, M., Djimde, A., Faucher, J., Genton, B., Guérin, P., Hamed, K., Hodel, E., Huang, L., Jullien, V., Karunajeewa, H., Kiechel, … Workman, L. (2015). BMC Medicine, 13(1).
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis
Abdulla, S., Ashley, E., Bassat, Q., Bethell, D., Bjorkman, A., Borrmann, S., D’Alessandro, U., Dahal, P., Day, N., Diakite, M., Djimde, A., Dondorp, A., Duong, S., Edstein, Fairhurst, R., Faiz, M., Falade, C., Flegg, J., Fogg, C., … Winstanley, P. (2015). Malaria Journal, 14(1).
Genomic epidemiology of the current wave of artemisinin resistant malaria
Amato, R., Miotto, O., Woodrow, C., Almagro-Garcia, J., Sinha, I., Campino, S., Mead, D., Drury, E., Kekre, M., Sanders, M., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Anderson, T., Andrianaranjaka, V., Apinjoh, T., Ashley, E., Auburn, S., Awandare, G., … MalariaGEN Plasmodium falciparum Community Project. (2015).